Improved Tablet Production by Modified Granulation Techniques – A Review

B. Venkateswara Reddy*, K. Navaneetha, P. Sandeep, P. Ujwala
Department of Pharmaceutics, St.Pauls College of Pharmacy, Turkayamjal , Hayathnagar , Ranga Reddy -501510

Abstract
Tablets are one of the oral solid dosage forms most widely used by the pharmaceutical manufacturers, physicians and patients due to the convenience in manufacturing, administration and suitability for delivery of most of the active ingredients. Tablets are manufactured by different methods such as wet granulation, dry granulation and direct compression. Granulation is defined as the size enlargement process in which fine and smaller particles are aggregated to form strong and stable particles called granules. Present article mainly focuses on advanced granulation techniques such as moisture activated dry granulation, thermal adhesion granulation, foam binder granulation etc.
Keywords: Tablets, Granulation, Direct compression, Moisture activated dry granulation, Foam binder granulation.