Foam Granulation an Advanced Technique of Granulation

M. Lavanya*, Naresh Gorantla, Rajesh Pawan, H Abdul Ahad
Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India.

A B S T R A C T
Granulation process is the most widely used technique for manufacturing materials for tablet in pharmaceutical industry. The methods, which include the granule formation, are microencapsulation, multi particulate system for modified release mechanism etc. Foam granulation technique involves addition of liquid binders in aqueous foam base. During foam granulation binders in aqueous form are added. More preferable over spray(wet) granulation. FGT is advantageous over wet granulation technique considering some factors like less water required for granulation, uniform distribution of binder, no over wetting of granules and no spray nozzle is required and most importantly suitable for water sensitive drugs. But Analysis of the foam allows small particles to adhere to larger particles in the early stages of granulation, and then get more completely agglomerated through the entire operation.
Keywords: Granulation, Spray, Foam, nozzle, binder and agglomeration.