Sunday , 3 March 2024

Development and In-vitro Assessement of Self Nano Emulsified Systems of Sertralline Hydrochloride

Vonteddu Sai Priya1, Syed Noorunnisa3, Perli Lakshmi Haritha4, E. Vijay Kumar*5
1,2,3,4,5Srinivasa Institute of Pharmaceutical Sciences, Proddatur, Andhra Pradesh, India

A B S T R A C T
Enhancing the bioavailability of BCS class II drugs is a great deal for the formulators to exploit their therapeutic advantages. Many of the techniques had been developed to enhance the solubility which been the rate limiting step for the proper bioavailability. In this study the technique of micro emulsification had been used to reach the objective for the enhancement of solubility of Sertralline hydrochloride an oral Antipyschotic drug. The use of surfactants to reduce the interfacial tension between the water and oil phase was studied in this work.

Keywords: Nano emulsions, SNEDDS, SMEDDS

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