Monday , 20 May 2024

Category Archives: Pharmaceutical Sciences and research inventions

Elucidation of In-Vitro and In-Vivo Cytotoxic Effects of Saffron in C1271 Breast Cancer Cells

Basharat Ali Malla1, Tahir Mohiuddin Malla2, Susan Manohar3, Narayanan Ganesh1* 1Department of Research Jawaharlal Nehru Cancer Hospital and Research Centre, Idgah Hills, Bhopal, M.P 2Cancer Diagnostic & Research Centre, Sher-i-Kashmir Institute of Medical Sciences, Srinagar (J&K) 3Department of Zoology Govt. MGM Post Graduate College, Itarsi, M.P. A BSTRACT Introduction: Breast cancer is second most common in women and accounts for ... Read More »

Analytical Method Development and Validation for the Determination of Brinzolamide and Brimonidine Using Reverse Phase HPLC Method in Bulk and Pharmaceutical Dosage Form

Dr R. Vani1*, Amena Samreen2, Humera Tabassum3, Dr M.sunitha4* 1Head of Department, Pharmaceutical Analysis and QA, Shadan Women’s College of Pharmacy, Hyderabad. 2Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad. 3Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad. 4Principal, Shadan Women’s College of Pharmacy, Hyderabad. ABSTRACT In RP-HPLC method, the conditions were optimized to obtain an adequate separation of eluted ... Read More »

Progeria: A Genetic and Rare Disease

Anitha Nandagopal*, Naaz Nazmeen, Firdous Afshan, Anupama Koneru Department of Pharmacology, Sultan-ul-Uloom College of Pharmacy, Road no.3, Banjara Hills, Hyderabad, Telangana-500034. ABSTRACT Hutchinson Gilford Progeria Syndrome is an extremely serious disorder characterized by rapid, premature ageing of children which can precipitate cardiovascular diseases. Progeria is caused by de novo mutation in Lamin A gene which activates splicing in donor site, ... Read More »

Analytical Method Validation for Essay of Emitricitabine, Rilpevirene and Tenofovir Alfanamide by RP-HPLC

Vasini Revathi, M. Shymala* Department of Analysis, Joginapally B.R. Pharmacy College, Yenkapally, Moinabad, Hyderabad, Telangana-500075 A B S T R A C T A new, simple, precise, accurate and reproducible RP-HPLC method for Simultaneous estimation of Emtricitabine and Tenofovir and Rilpivirine in bulk and pharmaceutical formulations. Separation of Emtricitabine and Tenofovir and Rilpivirine was successfully achieved on a Inertsil ODS ... Read More »

A Review on Cancer Therapy by Targeting HSP90

Shaik Salma Sultana*, P. Sukumari Jagan’s College of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India Abstract Chaperones (stress proteins) are essential proteins to help the formation and maintenance of the proper conformation of other proteins and to promote cell survival after a large variety of environmental stresses. Therefore, normal chaperone function is a key factor for endogenous stress adaptation ... Read More »

A Case Report on Sucralfate Induced Constipation

Neelam Swathi*, M. Swetha, Y. Himabindu, Ramesh Dhani IVth Pharm.D, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore, Andhra Pradesh, India. Abstract Mucosal protective agent are drugs that protects the mucosal lining of the stomach from acidic gastric juices. Sucralfate is a very safe and commonly prescribed drug indicated in the short term treatment of active duodenal ulcers, gastrointestional reflux disease, ... Read More »

Microextraction Techniques in Analysis of Drugs

Dr R. Vani1*, Rafia Tabassum2, Saba Khan3, Dr M.sunitha4* 1Head of Department, Pharmaceutical Analysis and QA, Shadan Women’s College of Pharmacy, Hyderabad 2Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad 3Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad 4Principal, Shadan Women’s College of Pharmacy, Hyderabad ABSTRACT Analytical methods comprise of a few stages including; examining, test preparation,analysis, figurings and measurable ... Read More »

An Inherited Genetic Blood Disorder: Thalassemia

D. Pragathi*, Ramesh Dhani, M. Gobinath Ratnam Institute of Pharmacy, Pidathapolur, Nellore, Andhra Pradesh, India Abstract Thalassemia is an inherited blood disorder characterized by less oxygen-carrying protein (haemoglobin) and fewer red blood cells in the body than normal. It is most common type of haemoglubinopathies transmittedby hereditary. It includes HBA1 and HBA2 genes. Alpha thalassemia involves in decreased alpha-globin production ... Read More »

Pharmacokinetic Evaluation of Transdermal Drug Delivery of Diclofenac Potassium In Human Volunteers

P. Kiranmayee, B. Kumar*, G. Tharunasree Department of Pharmacy Practice, Ratnam institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore District-524 346 Abstract Transdermal therapeutic systems are defined as self-contained discrete dosage forms which when applied to the intact skin, deliver the drugs through the skin, at a controlled rate to the systemic circulation.  To any drug moiety to elicit its pharmacological ... Read More »

A Review on Pharmacovigilance and Its Methodologies

*Suruchi Samparna Acharya, M. Ajay Kumar, A. Sai Kiran, P. Venkatesh Jagan’s College of Pharmacy, Jangalakandrika (V), Muthukur (M), SPSR Nellore (Dt), Andhra Pradesh- 524346. Abstract WHO (World Health Organisation) defines pharmacovigilance as science and activities relating to detection, assessment, understanding and prevention of adverse effects/ adverse drug reactions or any other medicine related problem[1] Pharmacovigilance is more than spontaneous ... Read More »

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