Sunday , 23 June 2024

Antidiabetic activity of Zizyphus xylopyrus Fruits

1Nidhi Suhane*, 2Deepa Singh
Daksh Institute of Pharmaceutical Science, Chhatarpur, M.P, India

Ziziphus xylopyrus is known for its medicinal properties for sore throats,  dysentery, inflammation of the uterus and as a anti-convulsant, Anti-Depressant, anti-inflammatory in all over world. This research was undertaken to test the effect ofZiziphus xylopyrus fruits extract on the diabetes of Rat. Ziziphus xylopyrus fruits extract (100 mg/kg, 200 mg/kg) was administered orally to Rat with the help of oral feeding needle. A total of 84 rats divided in 14 groups were employed in this study. Alloxan induced diabetes model was used in whole study. Serum total cholesterol, serum triglyceride, total protein, was also estimated before and after administration of fruits extract. Fruits extract was significantly (P < 0.001) reduce blood glucose level in alloxan induced diabetic rats. Fruits extract was significantly (P < 0.001) reduce total cholesterol level it also decrease (P < 0.001) triglyceride level. This drug was also increase (P < 0.001) total protein level.

Keyword: Diabetes, Blood glucose, Zizyphus xylopyrus, Kat-ber

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