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Antibacterial activity and Phytochemical Analysis of Acalypha indica L.

R. Bharathi1, K. Vasanthi1, Senthil kumarai Muthusamy1, C. Esaivani1 and K. Chairman2 
1Department of Zoology, Sri Parasakthi College for Women, Courtallam, M.S. University, Tirunelveli, Tamilnadu, India–627802
2Department of Microbiology, Kamarajar Arts College, Surandai, M.S. University, Tirunelveli, Tamilnadu, India–627859
Received: 21 August 2014, Accepted: 27 October 2014, Published Online: 15 December 2014

Acalypha indica is herb found in tropical countries. This is used traditionally for treating various diseases for centuries, including anti-bacterial and anti-fungal activities. Thus, the objective of this present investigation was to perform qualitative analysis of phytochemical compounds and also evaluate in vitro anti-bacterial activity of Acalypha indica. Crude ethyl acetate, petroleum ether and Toleune extract of leaves from Acalypha indica were tested for anti-bacterial activity against four bacterial species – Klebsiella pneumoniae, Salmonella typhi. Bacillus subtilis and Pseudomonas putida, It is inferred that ethyl acetate extract exhibited strong antibacterial activity with a maximum activity recorded against Klebsiella pneumoniae (22.67±0.33mm). The qualitative phytochemical screening indicated the presence of alkaloids, phenols saponins, steroids, flavonoids and catechol.
Keywords: Acalypha indica, antimicrobial activity, phytochemical constituents

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