P. Sailaja, M. Suchitra, K. Venkata Swapna, M. Abhinaya Priyanka, S. Malavika
Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore-524 346, Andhra Pradesh, India
The ethanolic extract of leaves of Mirabilis Jalapa Linn was investigated for anti-inflammatory activity in albino Wistar rats. The ethanolic extract administered by the oral route at a concentration of 200 and 400 mg/kg showed the significant dose dependent anti-inflammatory activity in carrageen in and Formalin-induced paw edema in rats. Anti-inflammatory activity of the tested extract was comparable with that of the standard drug Diclofenac sodium (40 mg/kg). The results lend support to the traditional use of in Mirabilis Jalapa Linn. the treatment of inflammatory diseases.
Key words: Mirabilis Jalapa Linn, ethanolic extract, albino Wistar rats, anti-inflammatory activity.