M. A. Nasseri*, E. Vahedi, B. Zakeri Nasab, A. Allahresani
Department of Chemistry, College of Sciences, University of Birjand, Birjand- 97175-615, Iran
A mild and green procedure is presented for the preparation of biologically interesting hydroxyl xanthones and hydroxyl thioxanthones via condensation of salicylic acid / thiosalicylic acid with phenol derivatives in the presences of ZrCl4 under microwave-assisted ionic liquid (MAIL) condition. This procedure offers several advantages including high yields, short reaction time, clean reaction and easy work-up which make it a useful and attractive strategy for the synthesis of xanthones and thioxanthones derivatives.
Keywords: Green Chemistry, Ionic Liquid, Hydroxy xanthone, Hydroxy thioxanthone, ZrCl4.