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Tag Archives: stress degradation

A New Validated Stability indicating RP-HPLC Method for the Quantitative Analysis of Phentermine Hydrochloride in Tablet Dosage Form

K.V. Lalitha*1, R. Kiranjyothi2 1Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research, Ananthapuramu – 515001, Andhra Pradesh, India. 2Department of Pharmaceutical Analysis, JNTUA – Oil Technological Research Institute, Ananthapuramu – 515001, Andhra Pradesh, India. A B S T R A C T A novel stability indicating RP-HPLC method was developed for the estimation of Phentermine hydrochloride in ... Read More »

Ketoconazole Solubility Enhancement: Different Techniques and its Comparison

Author Details Ravi Prakash*, Shashi Shekhar Tripathi, Pravin Gupta, Rahul Dev, Anaagat Sir Madanlal Institute of Pharmacy Aalampur Hauz, Etawah-206001, U.P., India Abstract Four techniques namely melt sonocrystallization, solid dispersion, hydrotrophy and inclusion complex with cyclodextrin were used for the solubility enhancement. The order of the techniques for the solubility enhancement was found hydrotrophy>inclusion complex>solid dispersion>sonocrystallization method. Enhancement in the ... Read More »

Stability indicating High Performance Thin Layer Chromatographic determination of Raloxifene Hydrochloride

Author Details Rajasekaran A*, Preethi N, Arivukkarasu R  Department of Pharmaceutical Analysis, KMCH College of Pharmacy, Coimbatore, India Abstract A simple, sensitive, selective, precise and stability indicating high-performance thin-layer chromatographic method was developed and validated for the determination of raloxifene hydrochloride as per the ICH guidelines. Precoated aluminium plates with silica gel 60F254 as the stationary phase and methanol: water: ... Read More »

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