Tuesday , 16 July 2024

Tag Archives: Dissolution

Bioavailiability Enhancement of BCS Class 4 Drugs: Key for Successful Formulations

ABOUT AUTHOR  Suhas.S Siddheshwar,  Ganesh.A.Waghmare, Prashant .B.Wadghule, Dattaprasad.N.Vikhe, Prajakta.S.Varpe Pravara Rural College of Pharmacy, A/P-Loni, Tal-Rahata, Dist. Ahmednagar, India-413736 Abstract Traditionally nearly 40% of the new chemical entities identified by pharmaceutical industry screening programmes have failed to be developed because of low solubility and low permeability which make formulation difficult or even impossible. The solubility issues complicating the delivery of ... Read More »

Formulation and Evaluation of Omeprazole Buccoadhesive Tablets: Effect of Polymers

ABOUT AUTHOR S. Prathyusha*, S. Prathima, K. Arshad Ahmed khan, C. Sowmya Ragavendra Institute of Pharmaceutical Education and Research, Anantapuramu, A.P, India. *E-mail: [email protected] Abstract For the development of omeprazole buccoadhesive tablets, we studied the release and bioavailability of omeprazole delivered by buccal adhesive tablets. These tablets composed of carbopol, xanthum gum, sodium cmc, Hpmc, sodium alginate, croscarmellose sodium. Croscarmellose ... Read More »

Method used for Solubility Enhancement of Poorly water Soluble Drug-A Review

About author Prasad Harendra*, Verma Navneet Kumar Rameshwaram Institute of technology and Management Lucknow, U.P. India E-mail: [email protected] Abstract The slow dissolution rate exhibited by poorly water-soluble drugs is a major challenge in the drug development process. Following oral administration, drugs with slow dissolution rates generally show erratic and incomplete absorption which may lead to therapeutic failure. The aim of ... Read More »

Pharmaceutical Process Engineering

Pharmaceutical Process Engineering Anthony J. Hickey David Ganderton Pharmaceutical manufacturing entails the combination of a number of unit processes. The major processes are described in this text. The efficiency, quality, and economy of manufacturing depend on an understanding of the individual operations involved in processing. In many cases—unlike in other types of industrial processing—safety and efficacy of a therapeutic agent ... Read More »

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