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Tag Archives: Pyrimidines

Synthesis of Some New Aminothiophene, Pyridazine, Pyrimidine and Thienopyrimidine Derivatives with expected biological activity

Ismail. M. M. Othman* Chemistry Department, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt. A B S T R A C T Treatment of 1 with active methylene reagents 2a, b and elemental sulfur furnished aminothiophene derivatives 3a, b. diazotization of 3a with active methylene compounds, namely malononitrile (5a) and acetylacetone (5b) afforded the corresponding hydrazono derivatives 6a, b. pyridazine ... Read More »

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