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Tag Archives: Solubility

Formulation and Evaluation of Atorvastatin Calcium Solid Dispersions

Mahitha P1, Charitha M, Krishna sumanth K, Yasasvi P,Madhumitha L, Prudhvi Raj V*, Niranjan babu M Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupathi-517561 A.P, India A B S T R A C T Atorvastatin is useful in converting bad cholesterol to good cholesterol. As this bad cholesterol causes many diseases in human like increase in cholesterol levels in ... Read More »

Formulation Development and Characterization of Rosuvastatin Inclusion Complexation

Saravanakumar K*, Sree Nagavalli K, Fayaz S, Vedhapriya C, Reshma S, Amulya J Department of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A.Rangampet, Tirupati-517102, Chittoor District, Andhra Pradesh, India. A B S T R A C T The present investigation is to study the influence of β-Cyclodextrin and hydroxy propyl β-Cyclodextrin on 1:1, 1:2 molar ratios of Rosuvastatin inclusion complexations which ... Read More »

Design, Characterization and Evaluation of Chrono-modulated Nateglinide using pulsatile Drug Delivery System

Angilicam Avinash*, Avula Sushma, Koneti Lalasa, Siddabathina Prasanth Kumar, Thumati Gowthami, Dr. M. Sreenivasulu Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh, India-524003. A B S T R A C T In present study pulsatile drug delivery system of nateglinide was developed to control early morning hyperglycemia to synchronize the circadian rhythm of diabetes mellitus. Nateglinide is a novel anti diabetic drug ... Read More »

Preparation and Evaluation of Solid Dispersions of Pioglitazone Using Skimmed Milk Powder as Carrier

A. Hemanth*1, H. Abdul Ahad2 1V. L .College of Pharmacy, Manik Prabhu Temple Road, Raichur-584103, India. 2Balaji College of Pharmacy, Rudrampeta Bypass, Anantapur-515001, India. A B S T R A C T Solubility is an important physicochemical factor affecting absorption of drug and its therapeutic effectiveness. Consequences of poor aqueous solubility would lead to failure in formulation development. The poor ... Read More »

Comparative study of different solvent extract of Olea dioica Roxb. Western Ghats, Karnataka, against selected plant and animal pathogenic bacteria

Ashwathanarayana.R*1, Raja Naika2  1Research student, Department of PG Studies and Research in Applied Botany, Jnanasahyadri, Kuvempu University, Shankaraghatta- 577451, Shimogga, district, Karnataka, India. 2Professor, Department of PG Studies and Research in Applied Botany, Jnanasahyadri, Kuvempu University, Shankaraghatta- 577451, Shimogga, district, Karnataka, India. A B S T R A C T Olea dioica Roxb. is a very important ethno medicinal evergreen tree ... Read More »

Solid Dispersion-A Strategy for Improving the Solubility of Lipophilic Drugs

Krishna Moorthy S.B,*1 Sandeep. J2, Rajalakshmi.R1, Rubiya SK1, Saddam hussain. SK1   1Department of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupathi, Andhra Pradesh, India. 517102. 2Department of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupathi, Andhra Pradesh, India. 517503. Abstract Improving oral bioavailability of drugs those given as solid dosage forms remains a challenge for the formulation scientists due to solubility ... Read More »

A Review on Liquisolid Technique

Alpesh Yadav1*, Isha Shah1, Patel Chirag J1, Patel Harnish K2, Patel Priyanka H3 1Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, India-302020. 2Editor-In-Chief, IJPRBS Journal, Gujarat, India. 3Director, Research Scholar Hub, Gujarat, India Abstract Poorly soluble, highly permeable active pharmaceutical ingredients represent a technological challenge because their poor bioavailability is only caused by poor water solubility resulting in low drug absorption. ... Read More »

Solubility Enhancement Techniques and Use of Dendrimers in the Solubilization of Water Insoluble and Poorly Soluble Drugs-A Review

Navneet Kumar Verma*1, Anubha Gupta1, Harendra Prasad2, Asha Roshan3, Shobhit Prakash Srivastava4, Vikash Chandra4  1Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow, (U.P), India 2Faculty of B. Pharmacy, CSM Group of Institution, Allahabad, (U.P), India 3R.K. College of Pharmacy, Azamgarh, (U.P), India 4Dr. M.C. Saxena College of Pharmacy, Lucknow, (U.P), India Received: 6 May 2014, Accepted: 12 June ... Read More »

Method used for Solubility Enhancement of Poorly water Soluble Drug-A Review

About author Prasad Harendra*, Verma Navneet Kumar Rameshwaram Institute of technology and Management Lucknow, U.P. India E-mail: [email protected] Abstract The slow dissolution rate exhibited by poorly water-soluble drugs is a major challenge in the drug development process. Following oral administration, drugs with slow dissolution rates generally show erratic and incomplete absorption which may lead to therapeutic failure. The aim of ... Read More »

Pharmaceutical Process Engineering

Pharmaceutical Process Engineering Anthony J. Hickey David Ganderton Pharmaceutical manufacturing entails the combination of a number of unit processes. The major processes are described in this text. The efficiency, quality, and economy of manufacturing depend on an understanding of the individual operations involved in processing. In many cases—unlike in other types of industrial processing—safety and efficacy of a therapeutic agent ... Read More »

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