Wednesday , 29 June 2022

Tag Archives: RP-HPLC

Method development and validation by RP-HPLC for the estimation of Zolmitriptan in bulk and its dosage form

About author D. Samson Israel*, D.Gowri Sankar,  K.Krishna Chaitanya, K.Balaram Kumar, K.Vinod University college of Pharmaceutical sciences, Andhra University, Visakhapatnam, A.P E-mail: samson.pharma@gmail.com Abstract Zolmitriptan is used in the acute treatment of migraine attacks. It was quantified by reverse phase HPLC equipped with Sunniest (C18, 150 x 4.6 mm, 5.0 µ) column and mobile phase using pH 8.5 buffer and methanol as organic modifiers ... Read More »

Method development and validation for the simultaneous estimation of Nebivolol hydrochloride and S (-) Amlodipine besilate in tablet dosage form by RP – HPLC

About author Prabhakaran. V.*, Sekar. S., Baskar.E., Raghuprasath. V.R. Formulation Research and Development Department, The Madras Pharmaceuticals, Karapakkam, Chennai, Tamil Nadu, India. Email: rnd@madraspharma.com ABSTRACT High Performance Liquid Chromatography method was developed and validated in a simple, specific and precise manner for Nebivolol HCl and Amlodipine besilate in a combined solid dosage form. Nebivolol hydrochloride, a long acting, cardioselective β ... Read More »

METHOD DEVELOPMENT AND ITS VALIDATION FOR QUANTITATIVE SIMULTANEOUS DETERMINATION OF DEXAMETHASONE AND GATIFLOXACIN IN OPHTHALMIC SOLUTION BY RP-HPLC

About author : Ankit Agarwal*, Subhash Dadhich, Sunil Kumar Tiwari, Kashyap Nagariya R & D Division, Ahlcon Parenterals (I) Ltd., Bhiwadi, Rajasthan, India *e-mail: ankitagarwal005@gmail.com ABSTRACT : To develop a simple, rapid and accurate HPLC method for simultaneous quantitative determination of Dexamethasone and Gatifloxacin in ophthalmic solution. Chromatographic separation was achieved with PDA detector using Inertsil C18, 250 x 4.6mm, ... Read More »

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