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Tag Archives: RP-HPLC

Method Development and Validation of Nebivolol by RP-HPLC

Naga Jyothi. C*, Gummi Vishwanth, P. Sunitha Pharmaceutical Analysis and Quality Assurance,   JNTUH, Kukutpally, Hyderabad, India A B S T R A C T An isocratic reversed-phase high performance liquid chromatographic method was established for the estimation of Nebivolol in tablet dosage form. The chromatographic conditions were successfully developed for the estimation of Nebivolol by using Develosil C18 column (150×4.6mm, ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Ambroxol HCL and Levocetrizine in Its Bulk and Dosage Form by RP-HPLC

R. Vivek*, Dr. T. Rama Mohan Reddy, Dr. V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Hyderabad, Rangareddy, India A B S T R A C T A simple Reverse phase liquid chromatographic method has been developed and subsequently validated for simultaneous determination of Levocetirizine and Ambroxol HCl in combination. The separation ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Albendazole and Ivermectin Tablet of Dosage Form by RP-HPLC

B. Saidulu*, G. Usha Sree, Dr. V. Uma Maheswara Rao Department of Pharmaceutical Analysis and Quality Assurance, CMR College of Pharmacy, Medchal, Hyderabad, Rangareddy, India A B S T R A C T A reverse phased liquid chromatography (LC) method was developed and validated for simultaneous estimation of albendazole and ivermectin in tablet dosage form. The isocratic LC analysis was ... Read More »

Development and Validation of RP-HPLC Method for the Quantitative Determination of Fexofenadine Hydrochloride in Tablet Dosage form

P. Rajamathi1, A. Chenthilnathan1* and A. Sathish babu2 1Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli–627 012, Tamil Nadu, India. 2The Madras Pharmaceuticals, Chennai – 600 096, Tamil Nadu, India. Abstract Fexofenadine hydrochloride is a non-sedative and selective peripheral H1 receptor antagonist used for allergic rhinitis and chronic urticaria. This paper deals with a simple, feasible and sensitive reverse-phase high-performance liquid ... Read More »

A Novel validated RP-HPLC method for the estimation of “Rupatadine” in its Bulk and Pharmaceutical Dosage forms

CH. Naveen Kumar*, Arvapalli Rajani, Vemula Madhavi Latha, Vijaya Kuchana Department of Pharmaceutical Analysis and Quality Assurance, Teegala Krishna Reddy College of Pharmacy, Hyderabad, India Abstract A Novel Reverse Phase High Performance Liquid Chromatography (RP-HPLC) method for the Estimation of “Rupatadine” has been developed. The developed method was found and proved to be a better one than the already existing ... Read More »

Development and Validation of Simultaneous Determination of Vitamins B1, B2, B3, B6 and Folic Acid in Multivitamin Tablet by RP-HPLC

A. Sankara Avudaiappan1, A. Chenthilnathan1* and S. Vikraman2  1Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli – 627 012, Tamil Nadu, India. 2Apex Laboratories Private Limited, Alathur, Kancheepuram District-603110 Tamil Nadu, India. Received: 29 April 2014, Accepted: 15 June 2014, Published Online: 27 July 2014 Abstract A simple, efficient and reproducible RP-HPLC method for simultaneous determination of vitamins B1 (Thiamine mononitrate), ... Read More »

Validated RP-HPLC Method for Simultaneous Estimation of Lisinopril and Hydrochlorothiazide in Combined Dosage forms

Author Details P. Nagaraju*, G. Indira Priyadarshini, SA. Bilal Ahmed and V. Siddhartha Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur–522 002, Andhra Pradesh, India. Abstract A rapid and sensitive reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for simultaneous estimation of Lisinopril and Hydrochlorothiazide. Chromatographic separation was achieved on reverse phase Agilent LC 1100 ... Read More »

Method development and validation of telmisartan and amlodipine besylate by RP-HPLC in Tablet Dosage form

Author Details MD. Ashraf Basha*, K. Mangamma, G. Mani kumar  Dept of Pharmaceutical Analysis and Quality Assurance, JNTU School of Pharmaceutical Sciences, Kakinada Abstract A simple, precise, accurate and rapid reverse phase high performance liquid chromatographic method had been developed for simultaneous estimation of Telmisartan and Amlodipine Besylate in tablet dosage form. SymmetryC18 4.6 x 250mm, 5m particle size was ... Read More »

Validated RP-HPLC Method for the Quantification of Anidulafungin In Bulk Sample and Parenteral Dosage Form and its Application to forced Degradation Studies in Bulk Sample

About author Lohita M*, Jaya Preethi P, Swetha K, Vengal Rao P, Naresh D, Amrutha V Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Sri Sainath nagar, Tirupati-517102. E-mail:  lohitapharma11@gmail.com Abstract A simple, selective, precise and stability-indicating high-performance liquid chromatographic method of analysis of Anidulafungin in pharmaceutical dosage form was developed and validated. The solvent system consisted of acetonitrile: water: 0.1% v/v ... Read More »

Method development and validation by RP-HPLC for the estimation of Zolmitriptan in bulk and its dosage form

About author D. Samson Israel*, D.Gowri Sankar,  K.Krishna Chaitanya, K.Balaram Kumar, K.Vinod University college of Pharmaceutical sciences, Andhra University, Visakhapatnam, A.P E-mail: samson.pharma@gmail.com Abstract Zolmitriptan is used in the acute treatment of migraine attacks. It was quantified by reverse phase HPLC equipped with Sunniest (C18, 150 x 4.6 mm, 5.0 µ) column and mobile phase using pH 8.5 buffer and methanol as organic modifiers ... Read More »

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