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Tag Archives: Permeability-lipophilicity

ABSORPTION AND DRUG DEVELOPMENT (Solubility, Permeability, and Charge State)

ALEX AVDEEF This is useful for the practicing pharmaceutical scientist involved in absorption–distribution–metabolism–excretion measurements who needs to communicate with medicinal chemists persuasively, so that newly synthesized molecules will be more ‘‘drug-like.’’ ADME is all about ‘‘a day in the life of a drug molecule’’ (absorption, distribution, metabolism, and excretion). Specifically, this book attempts to describe the state of the art ... Read More »

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