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Tag Archives: metformin

In Vitro Anti-Diabetic and Anti-Arthritic Activity of Hydro Ethanolic Extract of Cynodon Dactylon

K. Jyothsna Jayaraju*, Y. Meenakshi, R. Renuka Devi, P. Sravani, K. Murali Krishna, R. Leela Dr. K.V. Subba Reddy Institute of Pharmacy, Dupadu, Kurnool-518218, Andhra Pradesh, India A B S T R A C T Objective: The present study is aimed to evaluate the in-vitro anti-diabetic and anti-arthritic activity of hydro ethanolic extract of whole plant of Cynodon dactylon. Methods: ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Vildagliptin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Punna Venkateshwarlu*, CH. Shankar Department of Pharmaceutical Analysis, Vikas College of Pharmaceutical Sciences, Rayanigudem, Suryapet, Nalgonda, Telangana, India-508376 A B S T R A C T The chromatographic conditions were successfully developed for the separation of Metformin and Vildagliptin by using C18 Column (150 mm x 4.6 mm) 5 µm, flow rate was 1ml/min, mobile phase ratio was Methanol: Phosphate ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformine and Gemigliptin by RP-HPLC Method

Nair Ayana Ramesh1, Dr. D. Naresh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The estimation of metformin and gemigliptin was done by RP-HPLC. The Phosphate buffer was ... Read More »

Analytical Method Development and Validation for Elbasvir and Grazoprevir in Combine Phaarmaceutical Dosage forms by RP-HPLC

Abilash Reddy Vancha1, Dr. D. Naresh1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T HPLC is at present one of the most sophisticated tool of the ... Read More »

A New Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Empagliflozine and Metformin in its Pure and Pharmaceutical Dosage Forms

Sadiq Ali1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Gemigliptin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Y. Krishna Reddy*, Kedhareshwari, Y. Harikha, V. Harikrishna, Muzahid, K. Gopi Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Metformin and Gemigliptin by using RP-HPLC. The Phosphate buffer was pH 3.0 and the mobile phase was optimized with consists of Methanol: Phosphate buffer ... Read More »

Validated RP-HPLC Method for Simultaneous Estimation of Metformin and Vildagliptin in Its Tablets

Karem Kishore Kumar Reddy, Shaik Mohammed Yusuf*, E. Vijay Kumar, Bumireddy Pavani, E. Divya, Vummadi Sai Chandana Department of Pharmaceutical Analysis, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, rapid, sensitive and robust reversed phase-HPLC method was developed and validated to measure simultaneously the amount of Metformin and Vildagliptin ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformine Hydrochloride and Pioglitazone by Using UV Spectrophotometry

N. Geetha*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformine hydrochloride and Pioglitazone in Tablet dosage form. Chromatogram was run through C18, ... Read More »

Analytical Method Development and Validation for Sumultaneous Estimation of Metformine Hydrochloride and Pioglitazone by Using RP-HPLC

N. Geetha*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Pioglitazone in Tablet dosage form. Chromatogram was run through C18, 4.6 ... Read More »

Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles

B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »

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