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Tag Archives: metformin

Analytical Method Development and Validation for Elbasvir and Grazoprevir in Combine Phaarmaceutical Dosage forms by RP-HPLC

Abilash Reddy Vancha1, Dr. D. Naresh1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T HPLC is at present one of the most sophisticated tool of the ... Read More »

A New Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Empagliflozine and Metformin in its Pure and Pharmaceutical Dosage Forms

Sadiq Ali1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Gemigliptin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Y. Krishna Reddy*, Kedhareshwari, Y. Harikha, V. Harikrishna, Muzahid, K. Gopi Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Metformin and Gemigliptin by using RP-HPLC. The Phosphate buffer was pH 3.0 and the mobile phase was optimized with consists of Methanol: Phosphate buffer ... Read More »

Validated RP-HPLC Method for Simultaneous Estimation of Metformin and Vildagliptin in Its Tablets

Karem Kishore Kumar Reddy, Shaik Mohammed Yusuf*, E. Vijay Kumar, Bumireddy Pavani, E. Divya, Vummadi Sai Chandana Department of Pharmaceutical Analysis, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, rapid, sensitive and robust reversed phase-HPLC method was developed and validated to measure simultaneously the amount of Metformin and Vildagliptin ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformine Hydrochloride and Pioglitazone by Using UV Spectrophotometry

N. Geetha*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformine hydrochloride and Pioglitazone in Tablet dosage form. Chromatogram was run through C18, ... Read More »

Analytical Method Development and Validation for Sumultaneous Estimation of Metformine Hydrochloride and Pioglitazone by Using RP-HPLC

N. Geetha*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Pioglitazone in Tablet dosage form. Chromatogram was run through C18, 4.6 ... Read More »

Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles

B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »

Pharmacodynamic Drug Interaction of Anti-Hypertensive Drug Combination Metoprolol and Telmisartan on Combined Anti-diabetic Effect of Glimepiride and Metformin in Normal and Streptozotocin Induced Diabetic Rats

ABOUT AUTHOR  B. Kishore Kumar Reddy1*, K. Mohan1, C. Hari Kumar2, Dr. Hindustan Abdul Ahad3, B. Mohammed Ishaq3  1PG Department of Pharmacology, College of Pharmaceutical Sciences, Sri Krishnadevaraya University, Anantapur–515001, A.P. India. 2Department of Pharmacology, Vasavi College of Pharmacy, Bhakarapeta, Kadapa, A.P. India. 3Balaji College of Pharmacy, Anantapur–515001, A.P. India. Abstract Polytherapy is a useful tool for treating coexistent diseases, but ... Read More »

A Study on Drug-Drug Interaction between Anti-Hypertensive Drug Combination Amlodipine and Telmisartan on Anti-Diabetic Effect of Glimepiride and Metformin in Normal and Streptozotocin Induced Diabetic Rats

ABOUT AUTHOR B. Kishore Kumar Reddy1*, K. Mohan1, C. Hari Kumar2, Dr. Hindustan Abdul Ahad3, B. Mohammed Ishaq3 1PG Department of Pharmacology, College of Pharmaceutical Sciences, SriKrishnadevaraya University, Anantapur –515001, A.P. India. 2Department of Pharmacology, Vasavi College of Pharmacy, Bhakarapeta, KadapaDist, A.P. India. 3Balaji College of Pharmacy, Anantapur–515001, A.P. India. Abstract The aims of this study was to investigate the ... Read More »

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