Friday , 21 January 2022

Tag Archives: HPLC

HPLC Estimation of Levofloxacin in Bulk and Pharmaceutical Formulations

Rajkiran Kolakota*, Y. Rupavathi Department of Pharmaceutical Analysis, Sri Sivani College of Pharmacy, NH-16, Chilakapalem Jn, Srikakulam-532402, A.P ABSTRACT A HPLC method was developed and validated to determine trace amounts of levofloxacin related substances & degradation products in its formulation. Separation of levofloxacin from impurity A, impurity B, impurity C and unknown degradation products was achieved on a YMC-Pack Pro ... Read More »

A new RP-HPLC method development and validation for Simultaneous estimation of lumefantrine & artemether using bulk and Pharmaceutical Dosage Forms

Rajkiran Kolakota*, G. Sai Krishna Department of Pharmaceutical Analysis, Sri Sivani College of Pharmacy, NH-16, Chilakapalem Jn, Srikakulam-532402, A.P. A B S T R A C T A simple, rapid, accurate and precise isocratic reversed phase high performance liquid chromatographic method has been developed and validated for Simultaneous Estimation of Lumefantrine and Artemether in Combined Dosage Form. The chromatographic separation ... Read More »

A New RP-HPLC method developed and validated for the estimation of Tolterodine

Gobalakrishnan P*1, Munisekhar V, Hemanth Kumar V 1Department of Pharmaceutical Analysis, Vagdevi College of Pharmacy & Research Centre, Nellore, Andhra Pradesh, India. A B S T R A C T A rapid and sensitive RP-HPLC Method with UV detection (283nm) for routine analysis of Tolterodine in Bulk and in Pharmaceutical formulation was developed. Chromatography was performed with mobile phase containing ... Read More »

RP-HPLC Method Development and Validation for the Estimation of Olanzapine in bulk drug and tablet dosage form

Gobalakrishnan P*1, Munisekhar V, Hemanth Kumar V 1Department of Pharmaceutical Analysis, Vagdevi College of Pharmacy and Research Centre, Nellore, Andhra Pradesh, India. A  B  S  T  R A C T The methods developed for the determination of Olanzapine are simple, selective and offer the advantages of high sensitivity without the need for extraction.. A new method was developed for Stability ... Read More »

Analytical Method Development and Validation for Haloperidol and Seroquel Combine Pharmaceutical Dosage Forms by RP-HPLC

T.Anusha1, D. Naresh2, Gampa Vijay Kumar*3 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. ABSTRACT The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and ... Read More »

Novel validated reverse-phase chromatographic method for the stability-indicating studies of Tofacitinib dosage form

Birhanu Motbaynor* Haramaya University, College of Health and Medical Sciences, School of Pharmacy, Department of Pharmaceutical Chemistry, Harar, Ethiopia A  B  S  T  R A C T The objective of the current study was to develop and validate a rapid, precise, specific and stability-indicating reverse phase HPLC for the quantitative determination of TOFACITINIB in its dosage form. The determination is ... Read More »

Analytical Method Development and Validation for the Estimation of Brivaracetam in Bulk and Its Dosage Form by RP-HPLC

Patta Salomi*, S. Rama Thulasi, K. Ravindra Reddy P. Rami Reddy Memorial College of Pharmacy, Kadapa-516003, Andhra Pradesh, India ABSTRACT A simple reverse phase liquid Chromatographic method has been developed and subsequently validated for determination of Brivaracetam. The mobile composition of Potassium Dihydrogen orthophosphate (0.02M): Methanol 40:60v/v Buffer pH 6.0 adjusted with ortho phosphoric acid, waters column of C18 (250X4.6 ... Read More »

Development of Simple, Reliable, Rugged, Specific and Stability Indicating HPLC Methods for Quantification of Impurities in Canagliflozin

R. Suresh1*, Dr. Satyavir Singh 2, K. Subhash Chander Reddy3 1Research Scholar, 2Department of Science, OPJS University, Churu, Rajasthan. 2Department of Science, OPJS University, Churu, Rajasthan. 3Director Honour lab R&D, Bonthapalli, Hyderabad, Telangana. A  B  S  T  R A C T The aim of present research work development of simple, reliable, rugged, specific and stability indicating HPLC methods for quantification ... Read More »

RP-HPLC Method Development and Validation For Simultaneous Estimation of Aspirin and Clopidogrel In Bulk and Pharmaceutical Dosage Forms

B. Archana1, Dr. Gampa Vijay Kumar2* 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and economical for simultaneous estimation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ramucirumab and Paclitaxel by RP-HPLC Method

S. Srilatha1, B. Sravanthi2, Dr. Gampa Vijay Kumar3* 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A  B  S  T  R A C T The proposed HPLC method was ... Read More »

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