Wednesday , 7 June 2023

Tag Archives: aromatic aldehydes

Synthesis, Characterization and Biological Activity Evaluation of Some 2-(1, 1-Dimethyl Guanidinyl)-4,5-Diaryl Imidazoles

B. Geetha* Pharmacist, Plot No.1, H.No.8-3, SVU Non-Teaching Colony, Opposite Vidyanagar colony, Tirupati-517502 A B S T R A C T A series of 2-(1,1-dimethyl guanidinyl)-4,5-diaryl imidazoles are synthesized by condensing 2-hydroxy -1,2-diaryl ethanones with metformin. All the compounds were characterized and screened for their anthelminthic and anti-tubercular activity. Most of the compounds exhibit both the activities. Keywords: Aromatic aldehydes, ... Read More »

Synthesis and Characterization of 4-(2-Chlorobenzylidene)-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one

About author : Amee B. Patel & Pankaj S. Patel* Department of Chemistry, Sheth L.H. Science College, Mansa, India. Scholar of J.J.T. University, Jhunjhunu, Rajasthan. E-mail: Abstract : 4-(2-Chlorobenzylidene)-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one synthesized by the condensation of 1-(4-acetylphenyl)-4-(2-chlorobenzylidene)-2-phenyl-imidazol-5-one with various aldehydes in presence of ethanol. The intermediate 1-(4-acetylphenyl)-4-(2-chlorobenzylidene)-2-phenyl-imidazol-5-one synthesized by the condensation of  4-(2-chlorobenzylidene)-2-phenyl-1,3-oxazol-5-one  with 1-(4-aminophenyl) ethanone in presence of pyridine. ... Read More »

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