Spectral and Antimicrobial Studies of Some r(2), c(6)-diarylpiperidin-4- one cyanoaceticacid hydrazones

ABOUT AUTHOR 
S. Sivakumar^1,*, R. Arulraj²_, J. John Francis Xavier³, Hema Ramesh¹, K. Mageswari¹ , A. Rajappa^1 
1Department of Chemistry, Sri Manakula vinayagar Engineering College, Madagadipet,  Pondicherry-605107, India.
²Department of Chemistry, Bharathiar University, Coimbatore-641046,  India
³Department of Chemistry, Anna University campus, Panruti, India

Abstract
A novel synthesis of t(3)-Methyl-r(2),c(6)-diarylpiperidin-4-onecyanoaceticacidhydrazones 1–3were synthesized and Characterized by IR,  ¹H and ¹³C NMR spectral studies. The structures were investigated for antibacterial and antifungal activity. the observed vicinal proton-proton coupling constants suggest that 1-3 adopts chair conformation with the equatorial orientations of all substituent’s. 
Keywords: piperidin-4-onecyanoaceticacidhydrazone, Spectral, antibacterial, antifungal activity