K. Harinadha Baba, Perneti Sumaja Reddy*, Saritha Chandra
Narayana Pharmacy College, Chinthareddy Palem, Nellore-524003, Andhra Pradesh
A B S T R A C T
In recent years, there has been great interest in the use of stem cells for the treatment of neurological diseases. Thus, neurodegenerative disorders (e.g. Parkinson’s disease, Alzheimer’s disease, multiple sclerosis), vascular events (e.g. stroke) and traumatic diseases (e.g. spinal cord injury) have been admitted as incurable diseases. Different sources of cells for transplantation have been used, including neural progenitor cells, neural stem cells, or embryonic stem cells. In the last two decades the transplantation approach, by means of stem cells of different origin, has been suggested for the treatment of neurological diseases. A general strategy for stem cell transplantation to prevent or minimize neurological diseases is much more likely to be succeed. The present review deals with the introduction and historical aspects of stem cells, neurological disorders and stem cell therapy advancements.
Keywords: Stem cells, Neurological disorder, Transplantation, Neural stem cells, Embryonic stem cells