Relationship between thymosin β4 & IL-10 in systemic lupus erythematous patients correlated with (Sledai) in Kerbala Governorate

Hadi Rasool Hasan AL-Masoodi
Department of Clinical Laboratory Sciences, Pharmacy College, Kerbala University, Kerbala, Iraq.

A B S T R A C T
This study included study of thirty SLE female patients that diagnosed by clinic specialists by using (SLEDAI) taken from (Al- Hussein Medical City/Kerbala/ IRAQ) During the period March/2013 to April /2014. Control group consisted of 10 healthy woman who matched in age with patients, and haven’t history for this disease. The result  show a  significant  decreasing in concentration   of  thymosin-β 4  & circulating complement factors ( C3&C4) in active SEL patients compare in control while  IL-10 is predominantly an anti-inflammatory cytokine were significantly increased in SLE patients and to be associated with  anti ANA &-dsDNA antibodies and disease activity measured using the SLE Disease Activity Index (SLEDAI)
Keywords: Thymosin-β 4, circulating complement factors (C3&C4), SLE patients, IL-10