Wednesday , 11 December 2024

Novel Therapeutic Trends in Prevention and Management of Ovarian Cancer 

Surendra Katikala *, Ch. Varshitha, Shaik Anisa, M. Amarjothi
Swathi College of Pharmacy, Next to Nellore Toll Plaza, Venkatachalam  Mandal, Nellore, A.P-524320

A B S T R A C T
The ovaries are a pair of organs in the female reproductive system. They are in the pelvis, one on each side of the uterus (the hollow, pear-shaped organ where a fetus grows). Each ovary is about the size and shape of an almond. The ovaries make eggs and female hormones (chemicals that control the way certain cells or organs work in the body). The fallopian tubes are a pair of long, slender tubes, one on each side of the uterus. Eggs pass from the ovaries, through the fallopian tubes, to the uterus. Cancer sometimes begins at the end of the fallopian tube near the ovary and spreads to the ovary. The peritoneum is the tissue that lines the abdominal wall and covers organs in the abdomen. Primary peritoneal cancer is cancer that forms in the peritoneum and has not spread there from another part of the body. Cancer sometimes begins in the peritoneum and spreads to the ovary. Ovarian cancer is most common in postmenopausal women. From 2010 to 2019, the number of new cases of ovarian cancer decreased slightly each year. There was also a slight decrease in the number of deaths from ovarian cancer each year from 2011 to 2020. Women who have a family history of ovarian cancer and/or certain inherited gene changes, such as BRCA1 or BRCA2 gene changes, have a higher risk than women who do not have a family history or who have not inherited these gene changes. For women with inherited risk, genetic counseling and genetic testing can be used to find out more about how likely they are to develop ovarian cancer. It is hard to find ovarian cancer early. Early ovarian cancer may not cause any symptoms. When symptoms do appear, ovarian cancer is often advanced. Improving the prevention and early detection of ovarian carcinomas will be a critical component of reducing morbidity and mortality from ovarian cancer. The through understanding of risk factors has limited utility in accurately predicting risk at the individual level; thus, there is a clear need for improved and validated risk prediction models that can be used to screen the general population of women which would lower the ovarian cancer risk at the community.
Keywords: Ovaries, Ovarian cancer, fallopian tubes, gene changes, ovarian carcinomas ovarian cancer risk.

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