Friday , 20 May 2022

Method Development and Validation of Ondansetron in Bulk and Pharmaceutical Dosage Form by UV Spectrophotometer

P. Leena sruthi*, C. Ravindra Reddy, V. Sagarika, K. Girish, V. G. P. Sivakumar                         
Department of Pharmaceutical Analysis, Balaji College of Pharmacy, Anantapur–515001, AP, India

A B S T R A C T
A simple, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of ondansetron. The drug obeyed the Beer’s law and showed good correlation. It showed absorption maxima at 282 nm in distilled water. The linearity was observed between 5-40 µg/mL. The results of analysis were validated by recovery studies. The recovery was more than 99%. The proposed method can be used for the routine quality control testing of the marketed formulations.
Keywords: UV spectrophotometry, Ondansetron hydrochloride, distilled water, Tablets

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