Saturday , 8 May 2021

Liposomes for Targeted Drug Delivery: A Review

Sandeep. J*1 Shanmugam.V 1, Swaroopa.Y1, Krishna moorthy S.B2 
1Department of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupathi, Andhra Pradesh, India-517503.
2Department of Pharmaceutics, Sree Vidyanikethan College of Pharmacy, A. Rangampet, Tirupathi, Andhra Pradesh, India-517102.

Liposomes are result of self assembly of phospholipid in an aqueous media resulting in closed bilayered structures. Liposomes are one of unique drug delivery system which can be use in controlling and targeting drug delivery system. Liposomes are generally classified based upon structure, method of preparation, composition and application, conventional liposome, and specialty liposome. Liposomes are formulated and processed to differ in size, composition, charge and lamellarity, depending upon method of preparation either active loading technique or passive loading technique. The prepared liposomes are characterized for visual appearance, liposomal size distribution, lamillarity, liposome stability, entrapped volume and surface charges. Different marketed formulations are available in market for liposomes. The liposomes have many applications which increase its importance over other formulations.
Keywords: Liposomes, phospholipid, lamellarity, stability, entrapped volume.

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