Thursday , 28 March 2024

Green Synthesis of Fulgenic Acids via Aryl Aldehydes and Ketones from Stobbe Condensation Method

aYadav Hanuman Singh, bGadegone Sunita and cPande Hemant
bDepartment of Chemistry, Kamla Nehru Mahavidyalaya, Nagpur 440009, India
a,cDr. Ira Nimdeokar Research Center for Chemistry, Hislop College, Nagpur 440001, India

A B S T R A C T
One pot synthesis of acid esters by Stobbe condensation of alkylidene / arylidene succinates and aldehydes or ketones, their subsequent hydrolysis to diacids were reported. The Stobbe condensation of various aromatic aldehydes or ketones with dimethyl succinate gives different types of diacids [2a, (2Z,3Z)-2-3-bis(4-chlorophenyl) (phenyl) (methylene) succinic acid)], [2b,(2Z,3Z)-2-(4-chlorophenyl) (phenyl) (methylene)-3-(1-phenylethylidene) succinic acid], [2c, (2Z,3E)-2-3-bis(furan-2-ylmethylene) succinic acid)]through green approach. The improved yields of Fulgenic acid were observed by the green approach method as compared with other classical methods employed so far. 
Keywords: Green synthesis, Stobbe condensation, aryl aldehydes & ketones and their products.    

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