Qazi Zaid Ahmad*1, Aziz ur Rahman1, MD Imran Khan2, Tajuddin1
1Department of Saidla A.K. Tibbiya College AMU Aligarh, India
2Hamdard Laboratories, India
The present study was designed to evaluate the diuretic activity of Kabab chini (Piper cubeba) in albino rats. The powder of Kabab chini (Piper cubeba) were administered to the experimental rats orally at doses of 800 mg/kg/BW and 1200 mg/kg / BW / p.o. Furosamide (20 mg/kg) was used as standard drug in study. The diuretic effect of the test drug was evaluated by measuring urine volume, sodium, potassium and chloride content.Urine volume was significantly increased by the two doses of Kabab chini Piper cubeba in comparison to control group. Both the doses have exhibited dose dependent excretion of electrolytes when compared to control group. The elevated diuretic potential is statistically significant (P < 0.05) and comparable to that of standard diuretic agent.
Keywords: Diuretic activity, Kabab chini, (Piper cubeba), Unani Medicine