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Analytical Method Development and Validation for the Simultaneous Estimation of Risperidone and Trihexyphenidyl Hydrochloride by Using RP-HPLC method

Relangi Karun Kumar1*, Gope Edward Raju2, Kandregula Uma Maheswari3, Doonaboyina Raghava4, Kavala Nageswara Rao5 Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, Bhimavaram-534201, A.P, India Abstract A new method was established for simultaneous estimation of Risperidone and Trihexyphenidyl hydrochloride by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Risperidone and Trihexyphenidyl hydrochloride by using ThermosilC18 column ... Read More »

Analytical Method Development and Validation for Netupitant and Palonosetron in Combine Dosage form by RP-HPLC

Duvvani Pallavi1*, Gope Edward Raju2, Vaddi Lakshmi Priya3, Doonaboyina Raghava4, Kavala Nageswara Rao5 Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, Bhimavaram-534201, A.P, India A  B  S  T  R A C T High performance liquid chromatography is at present one of the most sophisticated tool for analysis. The estimation of Netupitant and Palonosetron was done by RP-HPLC. The assay of ... Read More »

Analytical Method Development and Validation for Ezetimibe and Rosuvastatin in API and Combine Pharmaceutical Dosage Forms by RP-HPLC

Dasari Teja1*, Gope Edward Raju2, V. Lakshmi Priya3, Doonaboyina Raghava4, Kavala Nageswara Rao5 Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, Bhimavaram-534201, A.P, India A b s t r a c t On the basis of experimental results, the proposed method is suitable for the quantitative determination of Rosuvastatin and Ezetimibe in pharmaceutical dosage form. The method provides great sensitivity, ... Read More »

Analytical Method Development and Validation for Velpatasvir and Sofosbuvir in Combined Dosage Form by RP-HPLC

Kaki Lily Grace1*, Gope Edward Raju2, Vaddi Lakshmi Priya3, Doonaboyina Raghava4, Kavala Nageswara Rao5 Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, Bhimavaram-534201, A.P, India Abstract High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation of Velpatasvir   and Sofosbuvirwas done by RP-HPLC. The Phosphate buffer was pH3.0 and the mobile phase was ... Read More »

A Novel strategies of progesterone: To improving the solid-state of dosage forms by co-crystallization process

Dharani. Muthukuru*, G. Sujatha, Dr. Y. Prapurna Chandra Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District – 524 346 Abstract Progesterone injection is oily because of its poor solubility. It is necessary to develop new dosage forms or delivery methods for Progesterone with nitrogen heterocyclic compounds (2,6-diaminopyridine, isonicotinamide, 4-aminopyridine, aminopyrazine, picolinamide and pyrazinamide) have been designed and ... Read More »

Method Development and Validation for Triprolidine and Phenylepherine in Bulk and Its Pharmaceutical Dosage Forms by Using RP-HPLC as per ICH Guidelines

Angara Ganesh1*, Gope Edward raju2, Vaddi Lakshmi Priya3, Doonaboyina Raghava4, Kavala Nageswara rao5 Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, Bhimavaram-534201, Andhra Pradesh, India A b s t r a c t High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation of Triprolidine and Phenylephrine was done by RP-HPLC. The ... Read More »

Analytical Method Development and Validation for Roflumilast and Montelukast in Combine Dosage Form by RP-HPLC

Peddinti Poojitha1*, Gope Edward Raju2, Kandregula Uma Maheswari3, Doonaboyina Raghava4, Kavala Nageswara Rao5 Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, Bhimavaram-534201, Andhra Pradesh, India A b s t r a c t The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and economical for simultaneous estimation of Roflumilast and Montelukast in tablet dosage form. The ... Read More »

Study of Comparision between Effectiveness and Tolerance of Angiotensineii Receptor Blockers and Betablockers in Cardiovascular Diseases

Ashwini*, Farheen, Triveni, Dr. Parameshwar Aleti, Dr. Karnakar Reddy Yalla S.R.R. College of Pharmaceutical Sciences, Valbhapur (V), Elkathurthy (M), Hanumakonda (D), Telangana A b s t r a c t AIM: The Aim of the study was to compare the Effectiveness and Tolerance of Angiotensin II Receptor Blockers and Beta -Blockers in Cardiovascular Diseases. Objectives: To find out Adverse drug ... Read More »

Review Article on Lassa Fever

V. Saichitraprathyusha* Ratnam Institute of Pharmacy, Pidathapoluru, Nellore District, Andhra Pradesh, India A B S T R A C T Lassa fever is endemic in west Africa, where it probably kills several thousand people each year. Lassa fever is a viral haemorrhagic fever transmitted by rats. It has been known since the 1950s, but the virus was not identified until ... Read More »

Comparative Haemovigilance Requirements of Brics Countries with that of USFDA and EMA Guidelines

E. Ravi Kumar*1, K. Sunil Kumar2 1Department of Pharmaceutics-DRA, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2Associate Professor, Department of Pharmaceutics-DRA, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A B S T R A C T Background: Transfusions are necessary for the management of variety of acquired and hereditary diseases, ... Read More »

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