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About author Abhilash A*, Prabhu Raj KJ, Gopi Krishna B, Hemalatha M, Dr. Hindustan Abdul Ahad B. Pharmacy, Balaji College of Pharmacy, Anantapur, AP, India. E-mail: [email protected] Abstract It has long been an integral part of school chemistry lessons – and a revision nightmare for students the world over.Now there is one more element to add to the periodic table ... Read More »
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Category Archives: Pharmaceutical Chemistry and New drug design
Biological Evaluation of Some Newly Synthsized Thiazolidinone Derivatives for their Analgesic Activity
About author Pravesh Gangwar*, Dr.Pankaj Sharma, Dr. Birendra Shrivastava. Jaya Sharma, Shikha Sharma Derartment of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India. E-mail: [email protected] Abstract Two new thiazolidinone derivatives were prepared by brominating 1-acetylnaphthalene in chloroform followed by condensation with substituted benzaldehyde thiosemicarbazones using ethanol to get 4-naphthalen-1-yl-2-{2-[(substituted phenyl)methylidene]hydrazino}-1,3-thiazoles. These thiazole derivatives were then cyclized to title compounds by ... Read More »
Synthesis and Characterization of New Thiazolidinone Derivatives and Screening for Their Anti-Inflamatory Activity
About author Pravesh Gangwar*, Dr.Pankaj Sharma, Dr. Birendra Shrivastava.Jaya Sharma, Shikha Sharma Department of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India. E-mail: [email protected] Abstract In the present study, a thiozolidinones derivatives were synthesized by the 1-actynaphthalene. 1-actynaphthalene on brominating with chloroform gives 1-bromoactynaphthalene which was reacted with substituted benzaldehyde thiosemicarbazone in ethanol as a solvent give 4-naphthalen-1-yl-2-{2-[(substituted phenyl) methylidene] ... Read More »
Synthesis, Characterization and Antioxidant studies of 2-Benzylthio benzimidazole derivatives
About author Sumayya K K*, Kamalabhai Amma V K, Babu G, Biju C R Department of Pharmaceutical Chemistry, Devaki Amma Memorial College of Pharmacy, Pulliparamba, Chelembra, Malappuram, India-673 634. *E mail: [email protected] Abstract The present study was undertaken to evaluate the antioxidant activity of some Mannich bases of 2-benzylthio benzimidazole derivatives. Mannich bases of 2-benzylthio benzimidazole were synthesized by formaldehyde, 2-benzylthio ... Read More »
Marine Organism: A Rich Source of Bioactive Metabolites
About author Nisha Choudhary*, Sunil Singh, Jyoti Rai, Inamullah, Surabhi Sharma Department of Pharmaceutical Chemistry, Invertis Institute of Pharmacy, Invertis University Bareilly (U.P) E-mail: [email protected] Abstract Natural products have proved to be a rich source of therapeutic agents. Plant extracts have been used for thousands of years in the treatment of human diseases. It is somewhat contradictory to note that most of ... Read More »
Estimation of Rabeprazole Sodium in tablet dosage form by using UV-VIS Spectrophotometer
About author Vipin Kumar Agrawal *, Alok Singh , Pravesh Kumar, Jyoti Rai, Inamullah Department of Pharmaceutics, Invertis Institute of Pharmacy, Invertis University, Bareilly-243 123, Uttar Pradesh, India Department of Pharmaceutical Chemistry, Invertis Institute of Pharmacy, Invertis University, Bareilly-243 123, Uttar Pradesh, India *E-mail: [email protected] Abstract Rabeprazole sodium (RSM) is a proton pump inhibitor used against peptic ulcer disease to ... Read More »
Role of DPP IV Inhibitor in Type-2 Diabetes Mellitus
About author : Anup K. Chakraborty*, Umesh K. Patil Dept of Pharmaceutical Chemistry, School of Pharmacy & Research Centre, People’s University, Bhopal (M.P.), India *e-mail: [email protected] Abstract: Incretin hormones are defined as intestinal hormones released in response to nutrient ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin effect is mainly caused by two peptide hormones, glucose-dependent insulin ... Read More »
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF SOME NOVEL BENZOIN DERIVATIVES
About author: P. Deepthi Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur,India E-mail: [email protected] INTRODUCTION :A natural product is a chemical compound or substance produced by a living organism – found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery, drug design. A natural product can be considered as such even if it ... Read More »
Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl(N-Me) Threonine
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: [email protected] ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the heterocyclic found ... Read More »
Synthesis and characterization of 3-[(5-phenyl hydroxyl-1, 3, 4-oxadiazol-2-yl) methyl amino]-2-methyl quinazolin-4(3h)-one
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, ... Read More »
