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M. A. Hameed Sadiq1*, Shoaib Patel2, Amol S. Dighe1, Rashmi D. Wani2, Bhagyashree P. Gaikwad2, Prashant Katiyar2, Shriram H. Bairagi2 1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, India- 413736. 2Department of Pharmaceutical Chemistry, Ideal College of Pharmacy & Research, Kalyan, India- 421306. A B S T R A C T Quinazoline is an aza derivative of the ... Read More »
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Category Archives: Pharmaceutical Chemistry and New drug design
Nephro-protective Activity of Methanol Extract of “Cassia tora” Seeds in Cisplatin Induced Nephrtoxicity in Mice
Raghuram Akinapelli*1, S.N Sri Harsha1, D. Yashwanth Kumar2 Faculty of Pharmacy, PACIFIC University, Udaipur, Rajasthan, India A B S T R A C T Kidneys have sensitive tasks, especially when they deal with unwanted substances, which have to be cleared from the system, principally toxins. Kidneys play an important role in the regulation of our endocrine and acid-base balance, erythropoiesis ... Read More »
Effct of Mechanochemically Synthesized Copper (II) and Silver (I) Complexes with Cefuroxime on Some Cephalosporin Resistance Bacteria
N. P. Ndahi1, M.B. Fugu1, I. Waziri1 and Y. A. Geidam2 1Department of Chemistry, University of Maiduguri, Maiduguri, Borno State, Nigeria 2Department of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria A B S T R A C T Complexation plays a vital role in drug development as a means of modifying the pharmacological, toxicological and physico-chemical properties of ... Read More »
Anticancer activity of Piperazine Propyl-4-Oxo-3,4-Dihydroquinazoline-2-Carboxylate Derivatives
A. Gopi Reddy1, V. Harinadha Babu1*, Y. Jaya Prakash Rao2 1Department of Pharmaceutical Chemistry, G. Pulla Reddy College of Pharmacy, Hyderabad. 2Department of Chemistry, Telangana University, Nizamabad, Telangana A B S T R A C T In this study, The synthesized piperazine propyl-4-oxo-3,4-dihydroquinazoline-2-carboxylate derivatives were screened for their in vitro anti proliferative activity in these four different human cancer cell ... Read More »
Antidermatophytic activity of alkaloid and saponin extracts from Cnidoscolus aconitifolius.
Basil Ita1*, Samuel Eduok2 1Department of Chemistry, University of Uyo, Uyo, Akwa Ibom State, Nigeria. 2Department of Microbiology, University of Uyo, Uyo, Akwa Ibom State, Nigeria. A B S T R A C T The antidermatophytic activity of saponin and alkaloid extracts from organs of Cnidoscolus aconitifolius against Trichophyton rubrum, Microsporum gypseum, Epidermophyton floccosum and Trichophyton interdigitale was studied by ... Read More »
A Review on Quinazolines as Anticancer Agents
A. Gopi Reddy*1, V. Harinadha Babu1*, Y. Jaya Prakash Rao2 1Department of Pharmaceutical Chemistry, G. Pulla Reddy College of Pharmacy, Hyderabad, India. 2Department of Chemistry, Telangana University, Nizamabad, India A B S T R A C T The present study was carried out on Zolmitriptan Mouth dissolving tablets were prepared by direct compression method and different concentration super disintegrants like ... Read More »
Evaluation of anthelmintic and In-vitro antioxidant Activities of plectranthus amboinicus
Garla Venkateswarlu*1, Dr. P. Venkatesh2, Dr. Hepcy kalarani3, E. Rajani4, M.P Vijay Kumar5 1Assistant professor, Dept. of pharmaceutical chemistry, Jagan’s College of Pharmacy, Nellore, A.P, India. 2Principal, Depatrment of pharmaceutical chemistry, Jagan’s College of Pharmacy, Nellore, A.P, India. 3HOD & Professor, Dept. of pharmaceutical chemistry, Jagan’s College of Pharmacy, Nellore, A.P, India. 4Assistant professor, Depatrment of pharmacology, Jagan’s College of ... Read More »
Synthesis and In-silico Studies of Novel Methylene Bridge Derivatives of Anthracene
G.T. Roopesh*, N. Sreelekha, P. Susmitha, P. Pallavi, M. Maniteja, B. Swapna Balaji college of pharmacy, Dept. of Pharmaceutical Chemistry Ananthapuramu, A.P, India. A B S T R A C T The present work was aimed to Synthesise and carryout Insilico studies of Methylene Bridge Derivatives of anthracene. Anthracene is mainly converted to anthraquinone, a precursor to dyes. The anthracene ... Read More »
Synthesis and Characterization of New Di Phenyl Quinoxaline Derivatives
C. Ramakrishna*, G. Saikrupa, S. Hanumantha rayappa, V. Visnu kumar, B. Swapna, S.Brahmani Bai, Dr. M. Geetha vani Balaji College of Pharmacy, Department of Pharmaceutical Chemistry Ananthapuramu, A.P, India. A B S T R A C T The heterocyclic compounds are very much used as anti microbial agents. Quinoxalines are an important class of nitrogen containing heterocyclic with wide variety ... Read More »
Synthesis Characterization and Anthelmintic Activity of Acid Hydrazides
C. Ramakrishna*, B. Sandhya, G. Saijyothi, D. Komala, G. Anveshkumar, Dr. M. Geetha Vani Balaji College of Pharmacy, Department of Pharmaceutical Chemistry, Ananthapuramu, A.P, India. A B S T R A C T Synthesis & evaluation acid Hydrazides and their derivatives for their anthelmintic activity was determined. Synthesized the acid Hydrazides derivatives (BPO-1 to BPC-4). When Hydrazides are conjugates with ... Read More »
