Antibacterial Activity of 2-(1H-benzo [D]imidazol-2-ylimino)-5-arylidenethiazolidin-4-ones, 1-(1H-benzo[d]imidazol-2-YL)-5-alkyl-3-aryl-1, 3,5-triazinane-2-thiones and 3-(1H-benzo[d]imidazol-2-yl)-5-aryl-1,3,5-oxadiazinane-4-Thiones

Karnaji Harkala^a, Laxminarayana Eppakayala*^a, Ramesh Domala^b and Thirumala Chary Maringanti^c*
^aMahatma Gandhi Institute of Technology, Chaitanya Bharati, Gandipet, Hyderabad, Telangana-500075
^bMahatma Gandhi University, Aneparti, Nalgonda, Telangana 508254
^cJawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad, Telangana -500 085

A B S T R A C T
The antibacterial activity of 2-(1H-benzo[d]imidazol-2-ylimino)-5-arylidenethiazolidin-4-ones, 1-(1H-benzo[d]imidazol-2-yl)-5-alkyl-3-aryl-1,3,5-triazinane-2-thiones and 3-(1H-benzo[d]imidazol-2-yl)-5-aryl-1,3,5-oxadiazinane-4-thiones have been investigated against  staphylococcus, Aureus Klebsiella Pneumoniae Salmonella Paratyphi A Salmonella Paratyphi B Micrococcus Luteus. The compounds have inhibited the spore germination of three fungi even at low doses. The compounds with chloro substituted were found to exhibit very high activity against all the bacteria.
Keywords: Antibacterial activity, thiazolidin-4-one, oxadiazinane, triazinane-2-thione and benzo[d]imidazole