Yasasvi P*, Sumanth K, Prudhvi Raj V
Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupathi.
A B S T R A C T
Valsartan is an angiotensin II receptor antagonist widely used in management in hypertension. The present research was aimed to develop a fast dissolving tablet (FDT) of valsartan. The FDT was formulated using different ingredients but the regularly used ingredients are sodium starch glycolate, crospovidine, these are the super disintegrants. The super disintegrants concentration is different based on the preparation method. The concentration for above disintegrants are (1,2and 4%) all the batches of (FDT) are prepared by direct compression method. The prepared valsartan should be evaluated for its physio-chemical properties. The drug release from FDTs increased with increasing concentration of super disintegrants and was found to be highest with formulations containing cross povidine.
Keywords: Valsartan, super disintegrants, fast disintegrating tablets