Y. Bhagyasri*, M.S. Divyasree, C.K. Ashok kumar, A. Nagamani Department of Pharmacognosy, Sree Vidyanikethan college of pharmacy, Rangampet, Tirupati-517102, Andhra Pradesh, Iindia.
A lot of medicinal plants, traditionally used for thousands of years, are present in a group of herbal preparations of the Indian traditional health care system named Rasayana proposed for their interesting antioxidant activities. Our country is a rich source of both biological and chemical diversity, which may be useful as a source of novel chemical structures. The timber value of Tectona grandis has been well known from decades. In The present study was meant to characterize pharmacological potential of different extracts from leaf, bark and stem of (Curcuma longa L., Abutilan indica L., Momordica charantia L., Solanum nigrum L., Tinospora cordifolia L., Abutilon indicum L.,) are viewed for their historical, etymological, morphological, Phytochemical and pharmacological aspects. The plants described contain antioxidant and anti-inflammatory principles. A comparative phytochemical analysis was carried to prove that the amount of phyto constituents varied with the fresh and dry stages of plants contributing to the activity of the extract. Total phenolic and saponnins content of both the extracts was estimated and was found to be more in the leaf, bark and stem giving positive results and the presence of steroids and Terpenoids also showed in leaf and stem. Antioxidant activity of extracts was carried out using ferulic acid and 2, 2-diphenyl-1- picrylhydrazyl (DPPH) assay and anti-inflammatory activity of the extract were also made. The anti-inflammatory activity was done by in-vivo model i.e. the carrageenan induced rat paw edema model, this extract reduced carrageenan induced rat paw edema in a dose dependent manner. This work stimulates the researchers for further research on the potential use of medicinal plant barks having anti-oxidant and anti-inflammatory property.
Key words: medicinal plant, anti-oxidant and anti-inflammatory activity, herbal extract