Navneet Kumar Verma*1, Anubha Gupta1, Harendra Prasad2
1Rameshwaram Institute of Technology and Management Lucknow (U.P), India
2CSM Group of Institution Allahabad, (U.P), India.
Liposomes are a novel drug delivery system (NDDS), in which the medication is encapsulated in a vesicle. It has been a study interest in the development of a NDDS. Liposomes are colloidal spheres of cholesterol non-toxic surfactants, sphingolipids, glycolipids, long chain fatty acids and even membrane proteins and drug molecules or it is also called vesicular system. It is differ in size, composition and charge. It is a drug carrier loaded with great variety of molecules such as small drug molecules, proteins, nucleotides and even plasmids. Few drugs are also formulated as liposomes to improve their therapeutic index. Consequently a number of vesicular drug delivery systems such as liposomes, niosomes, transfersomes, and pharmacosomes were developed. The focus of this review is to the various method of preparation, characterization of liposomes, advantages and brings out the application vesicular systems.
Keywords: NDDS, Liposomes, Vesicles, Colloidal spheres