Monday , 21 August 2017

Tag Archives: Validation

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Cefadroxil and Ambroxol Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India Abstract A Simple and rapid stability indicating RP-HPLC method was developed for the simultaneous determination of Cefadroxil and Ambroxol in bulk and pharmaceutical dosage form. A chromatographic separation of the two drugs was achieved with a Symmetry C18 (4.6 × 250 mm, 5 μm partical size, make: Xterra) ... Read More »

Design, Development and Validation of Bioanalytical Methods for Pharmaceutical Formulations – Review

Subramani1, M. Purushothaman*2 1Alwar College of Pharmacy, Sun Rise University, Alwar, Rajasthan – 301030, India 2Vasavi Institute of Pharmaceutical Sciences, Kadapa-516247, India A B S T R A C T Any method developed for the analysis of analytes in biological fluids must yield consistent results despite the variations in conditions during the course of a project. An ideal bioanalytical method ... Read More »

Method Development and Validation of Paracetamol, Guaifenesin, Ambroxol Hydrochloride, Phenylephrine Hydrochloride and Chlorpheniramine Maleate in Bulk and Combined Dosage Form Using RP-HPLC Technique

Swapnil B. Deshmukh*, Vilas L Badgujar, Priyanka N Chhajed, Trupti C. Mahajan, Tanvirahmad J. Shaikh DCS’S A.R.A College of Pharmacy, Nagaon, Dhule A B S T R A C T An RP-HPLC method for the simultaneous determination of Paracetamol, Guaifenesin, Ambroxol hydrochloride, Phenylephrine hydrochloride and Chlorpheniramine maleate in tablets was developed and validated ® as per ICH and FDA guidelines. ... Read More »

RP- HPLC Method Development and Validation for Simultaneous Estimation of Olopatadine and Montelukast

Sri Lakshmi D*1, Jane T Jacob2, Srinivaas Sastry D 1Department of Pharmaceutical Chemistry, Aditya Pharmacy College, Surampalem, Andhra Pradesh India. 2Nitte University, NGSMIPS, Department of Pharmaceutical chemistry, Mangalore, Karnataka, India. A B S T R A C T The aim of this work was focused on to develop and validate accurate, simple reverse phase high-performance liquid chromatography method for simultaneous ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms

Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms

Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India. A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »

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