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Tag Archives: Validation

RP-HPLC Method Development and Validation for the Simultaneous Estimation of Elbasvir and Grazoprevir Fixed dosage form

Purnacandra Rao Mendu* Department of Chemistry, Bundelkhand University, Jhansi, Uttar Pradesh, India A  B  S  T  R A C T The present research work focused on development and validation for the RP-HPLC method for the simultaneous estimation of Elbasvir and Grazoprevir in bulk and fixed dosage form. Chromatographic separation was achieved on by using Eclipse XDB -C18 (150×4.6mm, 5µm particle ... Read More »

Novel stability indicating RP-HPLC method for the determination of Ondansetron impurities in Ondansetron Injection

Dr. Srinivas Jagarlapudi*1, A. Ravi Kumar2, Panchumarthi Srinivas2, M. Raveendra Babu2, P. Ramyasree2 1Sri Krishnadevaraya University, Anatapuramu. Andhra Pradesh, India-515003. 2Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupathi, A. Ranganpet, Andhra Pradesh-517102.  A B S T R A C T The author developed a novel and unique RP-HPLC method for the determination of all the impurities of Ondansetron with ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage form by RP-HPLC

N. Kalpana Devi*1, Tirupathi Rao Velamala2, D.S.S.N.Neelima3 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Sulphadoxine and Pyrimethamine, in its pure form as well as in ... Read More »

Simultaneous Estimation of UV Spectroscopy and Method Development and Validation for Lansoprazole and Domperidone by RP-HPLC

Sanju Srinivas1, Marium Nazneen2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T A new method was established for simultaneous estimation of Lansoprazole and Domperidone  by  RP-HPLC method.   The chromatographic conditions were  successfully developed  for  the  separation  of  Lansoprazole and Domperidone by using ... Read More »

Simultaneous Estimation Method Development and Validated on Timolol Maleate and Brimonidine Tartrate by Using HPLC

1N. Kalpana Devi*, 2Sindhu Priya Mattepalli, 3D. S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad Telangana State 3Vikas Institite of Pharmaceutical Sciences – Rajahmundary ABSTRACT A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Timolol Maleate and Brimonidine Tartrate, in its pure form as well as in tablet dosage ... Read More »

Method Development and Validation of Brinzolamide and Brimonidine In Its Bulk And Ophthalmic Dosage Form By Using RP-HPLC

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, R.Hema3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A B ... Read More »

Validation of HPLC Method of Aceclofenac and Rabeprazole Sodiumin Aceclofenac Sustained Release and Enteric Coatedrabeprazole Sodium Capsules

Kalpana Patankar-Jain1, Parag Gadkari2, Pushkar Pradhan3 1Department of Chemistry, B. N. N. College, Bhiwandi 2Inventia Healthcare Pvt. Ltd., Thane 3Department of Chemistry, Ramnarain Ruia College, Mumbai A B S T R A C T The current research paper gives method validation report for the simultaneous quantification of Aceclofenac Sustained Release 200mg and Enteric Coated Rabeprazole 20mg capsules. The method involved ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Lumacaftor and Ivacaftor in Bulk and Pharmaceutical Dosage Forms

Rameeja Pattan*, V. Haribaskar, Pasala Sandhya Mounika, Ramesh Dhani, B. Prathap Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore A B S T R A C T A simple, fast, accurate, precise, reproducible Stability indicating Reverse phase High performance liquid chromatography (RP-HPLC) method was developed and validated for the determination of Lumacaftor and Ivacaftor in Bulk and ... Read More »

Simultaneous Estimation Method Development and Validated on Timolol Maleate and Brimonidine Tartrate by Using HPLC

1N.Kalpana Devi*, 2Sindhu Priya Mattepalli, 3D.S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad Telangana State 3Vikas Institite of Pharmaceutical Sciences – Rajahmundary ABSTRACT A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Timolol Maleate and Brimonidine Tartrate, in its pure form as well as in tablet dosage form. Chromatography was carried out ... Read More »

Analytical Method Development and Validation for Metoclopramide Hydrochloride by Using RP-HPLC

Meghnath chaudhary*, Dr. C. Sreedhar, T. Sreenivasarao, Katikala Dharmendra Department of Pharmaceutical analysis, Karnataka College of Pharmacy, 33/2, Thirumenahalli, Hegde Nagar Main Road, Jakkur Post, Bengaluru, Karnataka 560064 Abstract A simple, rapid, and sensitive high-performance liquid chromatographic method was developed and validated for determination of Metoclopramide Hydrochloride. Separation of Metoclopramide Hydrochloride was achieved within a single chromatographic run on an ... Read More »

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