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Tag Archives: RP-HPLC

Analytical Method Development and Validation for Pirfenidone (Anti-Fibrotic) in bulk drug and dosage form

Katikala Dharmendra*, Dr. C. Sreedhar, T. Sreenivasa Rao, Rikshaya Tamang, Meghnath Chaudhary, Mohamed adam Department of Pharmaceutical Analysis, Karnataka College of Pharmacy, #33/2,Thirumenahalli,Hegde Nagar main road, Bangalore – 560064, KA. India. A B S T R A C T Pirfenidone, 5-methyl-1-phenyl-2-(1H)-pyridine is a novel Anti-fibrotic agent approved for mild to moderate Idiopathic pulmonary fibrosis (IPF).  Isocratic reverse phase high performance ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Bupropion and Naltrexone in Bulk and Pharmaceutical Dosage Forms

Sanju Srinivas and V. Nirmala* Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana *Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T Thus the proposed stability indicating RP-HPLC technique for the synchronic determination of Naltraxone and Bupropione in bulk and pharmaceutical dosage form was accurate, precise, linear, reliable, simple, economic ... Read More »

Simultaneous Estimation of Amlodipine and Atenolol by Using Reverse Phase High Performance Liquid Chromatography in Bulk and Marketed Formulation

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India. Abstract A simple precise and accurate reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for the simultaneous estimation of Amlodipine and Atenolol. Chromatographic separation was achieved on Altima C18 column (4.6×150mm, 5µ) using the mobile phase consisting of Methanol: TEA ... Read More »

RP-HPLC Method for the Simultaneous Estimation of Ezetimibe and Atorvostatin in Bulk and Tablet Dosage Form

M. Madhuri1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management,   Rampally,   Kesara,   Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Ezetimibe and Atorvastatin by RP-HPLC method. The ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Celecoxib and Diacerein in Bulk and Pharmaceutical Dosage Form Using RP-HPLC

Ameena Parveen1*, Dr. R. Vani2, Dr. M. Sunitha 1Post-graduate student, Shadan Women’s College of Pharmacy, Hyderabad, India 2Head of the department, Pharmaceutical Analysis, Shadan Women’s College of Pharmacy, Hyderabad 3Principal, Shadan Women’s College of Pharmacy, Hyderabad, India A B S T R A C T A new simple, accurate, precise and reproducible RP-HPLC method has been developed for the simultaneous ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form

V. Haribaskar, Ramesh Dhani, B. Swathi* Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, 5µ with flow rate 1ml/min using ... Read More »

Reverse Phase High Performance Liquid Chromatographic Technique for the Determination of Rabeprazole in Pure and It’s Dosage Form

Dr. Hareesh Dara*, Meesa Rajendar St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana. A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Rabeprazole, in its pure form as well as in tablet dosage form. Chromatography was carried out on a Symmetry C18 (4.6 ... Read More »

Method Development and Validation for the Quantitative Estimation of Citalopram in Bulk and Pharmaceutical Tablets by RP-HPLC

Bushra Nazeer and P. Bharath Rathna Kumar* Department of Pharmaceutical Analysis & Quality Assurance, Anwarul Uloom College of Pharmacy, New Mallepally, Hyderabad, Telangana, India. A B S T R A C T In this study, a simple, precise and accurate reverse phase high performance liquid chromatography was developed for the estimation of citalopram in bulk and pharmaceutical dosage forms. A ... Read More »

Development of new RP-HPLC Method for Qualitative and Quantitative Analysis of Haloperidol and Lorazepam

Pakir Pranaya* Guru Nanak Institute of Pharmacy, Ibrahimpatnam, Rangareddy, Telangana, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Haloperidol and Lorazepam by using ACE C18 column (4.6×150mm) 5µ, flow rate was 1.2 ml/min, mobile phase ratio was (70:30 v/v) methanol: Phosphate buffer pH 3 (pH was adjusted with orthophosphoricacid), ... Read More »

Analytical Method Development and Validation for Rilpivirine and Dolutegravir in Combine Dosage Forms by RP- HPLC

Pakir Pranaya* Guru Nanak Institute of Pharmacy, Ibrahimpatnam, Rangareddy, Telangana, India  A B S T R A C T The chromatographic conditions were successfully developed for the separation of Rilpivirine and Dolutegravir by using ACE C18 column (4.6×150mm) 5µ, flow rate was 1.2 ml/min, mobile phase ratio was (70:30 v/v) methanol: Phosphate buffer pH 3 (pH was adjusted with orthophosphoricacid), ... Read More »

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