Saturday , 25 November 2017

Tag Archives: RP-HPLC

Development of New Validated Stibility Indicating RP-HPLC Method for the Simultaneous Estimation of Rosuvastatin and Aspirin in Bulk and Pharmaceutical Dosage Form

Ramesh Dhani*, V. Haribaskar, G. Guramjyothi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India Abstract Simple precise and accurate method was developed for the estimation of Rosuvastatin and Aspirin. The mobile phase consisting of 0.01N Phosphate buffer 32 as mobile phase A and acetonitrile 68 as mobile phase B gave retention time for Rosuvastatin and Aspirin ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and `Pharmaceutical Dosage Form

V. Haribaskar*, Ramesh Dhani, B. Swathi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India Abstract Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, 5µ with flow rate 1ml/min using PDA detection at 235 nm. The estimation ... Read More »

Stability indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Metformin and Teneligliptin in Pharmaceutical Formulation

Ramesh Dhani*, V. Haribaskar, J. Priyanka Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India Abstract A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Teneligliptin in pharmaceutical dosage form. Chromatogram was run through ODS2 C18 (4.6 x 200mm, 10.0mm) column. Mobile phase containing 50% Buffer and 50% Acetonitrile was pumped ... Read More »

Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Dutasteride and Tamsulosin Hydrochlochloride in Pharmaceutical Formulation

V. Haribaskar*, Ramesh Dhani, V. Sravanthi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India Abstract: A simple, Accurate, precise method was developed for the simultaneous estimation of the Dutasteride and Tamsulosin hydrochloride in Capsule dosage form. Chromatogram was run through Dionex,C18 (250×4.6mm), 5µ column. Mobile phase containing Methanol and Buffer (100 mM dipotassium hydrogen phosphate with pH ... Read More »

Development and Validation of a RP-HPLC Method for the Determination of Acyclovir in Transdermal Patches

R. Venu Priya1 and Vinesh Kumar2 1Research Scholar, Sun Rise University, Alwar, Rajasthan, India. 2Department of Pharmacy, Sun Rise University, Alwar, Rajasthan, India. A B S T R A C T The present report describes a rapid and sensitive High Pressure Liquid Chromatography (HPLC) method with UV detection to quantify acyclovir in transdermal patches. After sample preparation with diluent separation ... Read More »

Validation of Developed Analytical Method for Valsartan Floating Tablets by Reverse Phase High Performance Liquid Chromatography

C. Saravanan*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T Aim of the present investigation was to validate a new analytical, simple, sensitive, selective and precise High Performance Layer Chromatograpic (HPLC) method for the estimation of Valsartan in ... Read More »

Method Development and Validation of Omeprazole by RP-HPLC Method in Bulk and Its Pharmaceutical Dosage Form

Nagadani Kalyani*, R. Kiran Jyothi, Dr. K.B Chandra Sekhar Department of Pharmaceutical Analysis, JNTUA- Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515001, A. P, India A B S T R A C T Omeprazole is a proton pump inhibitor ﴾PPI﴿ and a potent inhibitor of gastric acidity which is mostly used in the therapy of gastroesophageal reflux and peptic ulcer disease. ... Read More »

A New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Emtricitabine and Tenofovir Disoproxil Fumarate in Bulk Drug and Pharmaceutical Dosage Form

M. Bharathi*, P. Rameeja, V. Haribaskar, Ramesh Dhani, B. Swathi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Emtricitabine and Tenofovir disoproxil. The mobile phase consisting 80% buffer 20% Acetonitrile. The column was used Inertsil ODS ... Read More »

Development of New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Rosuvastatin and Aspirin in Bulk and Pharmaceutical Dosage Form

G. Gurum Jyothi, Ramesh Dhani*, V. Hari Baskar, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Rosuvastatin and Aspirin. The mobile phase consisting of 0.01N Phosphate buffer 32 as mobile phase A and ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form

B. Swathi, V. Hari Baskar*, Ramesh Dhani, M. Bharathi, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, ... Read More »

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