Thursday , 15 November 2018

Tag Archives: RP-HPLC

Simultaneous Estimation of Moxonidine and Hydrochlorothiazide in Tablets by RP-HPLC

A. Thenmozhi, H. Mubeena*, N. Venkateshan Department of Pharmaceutical Analysis, Arulmigu Kalasalingam College of Pharmacy, Anand Nagar, Krishnankoil -626 190, Tamil Nadu. A  B  S  T  R  A  C  T A simple, precise, specific sensitive and accurate reverse phase high performance liquid chromatographic (HPLC) method was developed for the determination of Moxonidine and Hydrochlorothiazide in tablet dosage form. The separation ... Read More »

Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Pharmaceutical Dosage Form

D. Hemalatha, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, A.P, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ledipasvir and Sofosbuvir in bulk and its  Tablet dosage form. Chromatogram was run through Std Kromosil C18 (150 x 4.6 mm, 5m) column. Mobile phase containing Buffer 0.01N KH2PO4: Acetonitrile taken ... Read More »

Simultaneous Estimation Method Development and Validated on Timolol Maleate and Brimonidine Tartrate by Using HPLC

1N.Kalpana Devi*, 2Sindhu Priya Mattepalli, 3D.S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad Telangana State 3Vikas Institite of Pharmaceutical Sciences – Rajahmundary ABSTRACT A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Timolol Maleate and Brimonidine Tartrate, in its pure form as well as in tablet dosage form. Chromatography was carried out ... Read More »

RP-HPLC Method Development and Validaton for the Simultaneous Estimation of L-Methyl Folate and EscitalopramIn Bulk and Its Pharmaceutical Dosage Form

Guvvala Triveni, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, Andhra Pradesh, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the L-methyl folate and Escitalopram in bulk and its pharmaceutical dosage form.Chromatographic separation was carried on Denali C18(150 x 4.6 mm, 5µ) column . Mobile phase consist of Phosphate buffer and ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Lumacaftor and Ivacaftor in Bulk and Pharmaceutical Dosage Forms

Pasala Sandhya Mounika, Rameeja Pattan* Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore ABSTRACT A simple, fast, accurate, precise, reproducible Stability indicating Reverse phase High performance liquid chromatography (RP-HPLC) method was developed and validated for the determination of Lumacaftor and Ivacaftor in Bulk and pharmaceutical dosage form. Chromatographic separation was  done  by using Agilent Eclipse XDB-C8 column ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Sofosbuvir and Velpatasvir in Bulk and Pharmaceutical Dosage Form

P. Priyanka, Ramesh Dhani*, M. Suchitra Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore. ABSTRACT A simple, precise, accurate rp-hplc method has been developed and validated for the sofosbuvir and velpatasvir in bulk and pharmaceutical dosage form. This method was carried out by using Inertsil ODS-3(4.6 x 150mm, 5mm).  Mobile phase containing phosphate buffer (ph4.8): Acetonitrile (35:65) at ... Read More »

Analytical Method Development and Validation for Pirfenidone (Anti-Fibrotic) in bulk drug and dosage form

Katikala Dharmendra*, Dr. C. Sreedhar, T. Sreenivasa Rao, Rikshaya Tamang, Meghnath Chaudhary, Mohamed adam Department of Pharmaceutical Analysis, Karnataka College of Pharmacy, #33/2,Thirumenahalli,Hegde Nagar main road, Bangalore – 560064, KA. India. A B S T R A C T Pirfenidone, 5-methyl-1-phenyl-2-(1H)-pyridine is a novel Anti-fibrotic agent approved for mild to moderate Idiopathic pulmonary fibrosis (IPF).  Isocratic reverse phase high performance ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Bupropion and Naltrexone in Bulk and Pharmaceutical Dosage Forms

Sanju Srinivas and V. Nirmala* Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana *Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T Thus the proposed stability indicating RP-HPLC technique for the synchronic determination of Naltraxone and Bupropione in bulk and pharmaceutical dosage form was accurate, precise, linear, reliable, simple, economic ... Read More »

Simultaneous Estimation of Amlodipine and Atenolol by Using Reverse Phase High Performance Liquid Chromatography in Bulk and Marketed Formulation

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India. Abstract A simple precise and accurate reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for the simultaneous estimation of Amlodipine and Atenolol. Chromatographic separation was achieved on Altima C18 column (4.6×150mm, 5µ) using the mobile phase consisting of Methanol: TEA ... Read More »

RP-HPLC Method for the Simultaneous Estimation of Ezetimibe and Atorvostatin in Bulk and Tablet Dosage Form

M. Madhuri1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management,   Rampally,   Kesara,   Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Ezetimibe and Atorvastatin by RP-HPLC method. The ... Read More »

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