Saturday , 23 September 2017

Tag Archives: RP-HPLC

Validation of Developed Analytical Method for Valsartan Floating Tablets by Reverse Phase High Performance Liquid Chromatography

C. Saravanan*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T Aim of the present investigation was to validate a new analytical, simple, sensitive, selective and precise High Performance Layer Chromatograpic (HPLC) method for the estimation of Valsartan in ... Read More »

Method Development and Validation of Omeprazole by RP-HPLC Method in Bulk and Its Pharmaceutical Dosage Form

Nagadani Kalyani*, R. Kiran Jyothi, Dr. K.B Chandra Sekhar Department of Pharmaceutical Analysis, JNTUA- Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515001, A. P, India A B S T R A C T Omeprazole is a proton pump inhibitor ﴾PPI﴿ and a potent inhibitor of gastric acidity which is mostly used in the therapy of gastroesophageal reflux and peptic ulcer disease. ... Read More »

A New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Emtricitabine and Tenofovir Disoproxil Fumarate in Bulk Drug and Pharmaceutical Dosage Form

M. Bharathi*, P. Rameeja, V. Haribaskar, Ramesh Dhani, B. Swathi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Emtricitabine and Tenofovir disoproxil. The mobile phase consisting 80% buffer 20% Acetonitrile. The column was used Inertsil ODS ... Read More »

Development of New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Rosuvastatin and Aspirin in Bulk and Pharmaceutical Dosage Form

G. Gurum Jyothi, Ramesh Dhani*, V. Hari Baskar, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Rosuvastatin and Aspirin. The mobile phase consisting of 0.01N Phosphate buffer 32 as mobile phase A and ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form

B. Swathi, V. Hari Baskar*, Ramesh Dhani, M. Bharathi, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformin, Pioglitazone and Glimepiride in Combined Tablet Dosage Form by using RP-HPLC

M.D. Fiaz*, Dr. R. Vani, Dr. Iffath Rizwana Post graduate student, Deccan School of Pharmacy, Hyderabad, Telangana, India. University of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Metformin, Pioglitazone and Glimepiride in Tablet dosage form by using RP-HPLC method. Methods: ... Read More »

Development and Validation of RP-HPLC Method for Simultaneous Determination of Donepezil and Memantine in their Tablet Dosage Forms

Srinivas Ganta*, Vidyadhara S Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur-522018, Andhra Pradesh, India. A B S T R A C T A simple, accurate and specific RP-HPLC method has been developed and validated for the simultaneous estimation of Memantine (MEM) HCl and Donepezil (DON) HCl in bulk and pharmaceutical dosage form. Chromatographic separation was achieved on Symmetry C18 ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Glibenclamide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Ramanjaneyaulu*, Devika Subrramaniyan.G, Ramesh petchi Rajendran Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Glibenclamide in bulk and Pharmaceutical dosage form. The separation was acheived by using C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio ... Read More »

Evaluation of Analgesic Activity and Anti-Epileptic Activity of Ether Leaf Extract of Guggul

K. N. S. Karthik, Konda Ravi Kumar* Department of Pharmaceutical Chemistry, Hindu college of Pharmacy, Amaravathi Road, Guntur. Andhra Pradesh, India. A B S T R A C T Commiphora mukul is a flowering plant in the family Burseraceae. It is a shrubor small tree, attaining maximum height of 4 m, with thin paper y bark and thorny branches. The ... Read More »

Method Development and Validation of Mycophenolate Mofetil by RP-HPLC

Rubina Kauser, M. Mushraff Ali Khan, Airaj Mahajabeen, Farhana Shaheen, Salma Begum MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »

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