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Tag Archives: RP-HPLC

Method Development and Validation of Artemether and Lumifantrine by RP-HPLC

Farhana Shaheen*, Rubina Kauser, Salma Begum, Airaj Mahajabeen, Md Fasiuddin MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Introduction Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the immobilized ... Read More »

Method Development and Validation of Paracetamol, Guaifenesin, Ambroxol Hydrochloride, Phenylephrine Hydrochloride and Chlorpheniramine Maleate in Bulk and Combined Dosage Form Using RP-HPLC Technique

Swapnil B. Deshmukh*, Vilas L Badgujar, Priyanka N Chhajed, Trupti C. Mahajan, Tanvirahmad J. Shaikh DCS’S A.R.A College of Pharmacy, Nagaon, Dhule A B S T R A C T An RP-HPLC method for the simultaneous determination of Paracetamol, Guaifenesin, Ambroxol hydrochloride, Phenylephrine hydrochloride and Chlorpheniramine maleate in tablets was developed and validated ® as per ICH and FDA guidelines. ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril and Hydrochlorothiazide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Jyothi Keerthi*, G. Devika Subramaniyan, Ramesh Petchi, Rajendran Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A Reverse Phase High Performance Liquid Chromatography method was developed for the determination of Enalapril and Hydrochlorothiazide in bulk and Pharmaceutical dosage form. The separation was achieved on an Inertsil ODS (250×4.6mm),5µm column by using a ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ivacaftor and Lumacaftor in its Bulk and Pharmaceutical Dosage Forms

Satheesh1, Dr. D. Naresh2, P.Sowjanya3, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Ivacaftor and Lumacaftor by RP-HPLC method.  ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformine and Gemigliptin by RP-HPLC Method

Nair Ayana Ramesh1, Dr. D. Naresh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The estimation of metformin and gemigliptin was done by RP-HPLC. The Phosphate buffer was ... Read More »

A Validated RP- HPLC Method for the Simultaneous Estimation of Empagliflozin and Linagliptin in its Bulk and Pharmaceutical Dosage Forms

Jayalaxmi1, Dr. T. Rajesh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Empagliflozin and Linagliptin by RP-HPLC method. The ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

Analytical Method Development and Validation for Elbasvir and Grazoprevir in Combine Phaarmaceutical Dosage forms by RP-HPLC

Abilash Reddy Vancha1, Dr. D. Naresh1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T HPLC is at present one of the most sophisticated tool of the ... Read More »

A New Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Empagliflozine and Metformin in its Pure and Pharmaceutical Dosage Forms

Sadiq Ali1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation ... Read More »

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