Monday , 19 February 2018

Tag Archives: RP-HPLC

RP-HPLC Metthod Development and Vaidation for Velpatasvir and Voxilaprevir by Simulatneous Determination in Bulk and Their Pharamceutical Dosage Forms

MD. Abdul Sattar*, A. Suneetha Department of Pharmaceutical Analysis, Hindu college of Pharmacy, Amaravathi Road, Guntur-522002, A. P, India. A B S T R A C T Chromatography is the most powerful and versatile technique available to the modern analyst. In a single step process it can separate a mixture into its individual components and simultaneously provide a quantitative estimate ... Read More »

Development and Validation of a RP-HPLC Method for the Determination of Acyclovir in Transdermal Patches

R. Venu Priya1 and Vinesh Kumar2 1Research Scholar, Sun Rise University, Alwar, Rajasthan, India. 2Department of Pharmacy, Sun Rise University, Alwar, Rajasthan, India. A B S T R A C T The present report describes a rapid and sensitive High Pressure Liquid Chromatography (HPLC) method with UV detection to quantify acyclovir in transdermal patches. After sample preparation with diluent separation ... Read More »

Validation of Developed Analytical Method for Valsartan Floating Tablets by Reverse Phase High Performance Liquid Chromatography

C. Saravanan*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T Aim of the present investigation was to validate a new analytical, simple, sensitive, selective and precise High Performance Layer Chromatograpic (HPLC) method for the estimation of Valsartan in ... Read More »

Method Development and Validation of Omeprazole by RP-HPLC Method in Bulk and Its Pharmaceutical Dosage Form

Nagadani Kalyani*, R. Kiran Jyothi, Dr. K.B Chandra Sekhar Department of Pharmaceutical Analysis, JNTUA- Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515001, A. P, India A B S T R A C T Omeprazole is a proton pump inhibitor ﴾PPI﴿ and a potent inhibitor of gastric acidity which is mostly used in the therapy of gastroesophageal reflux and peptic ulcer disease. ... Read More »

A New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Emtricitabine and Tenofovir Disoproxil Fumarate in Bulk Drug and Pharmaceutical Dosage Form

M. Bharathi*, P. Rameeja, V. Haribaskar, Ramesh Dhani, B. Swathi Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Emtricitabine and Tenofovir disoproxil. The mobile phase consisting 80% buffer 20% Acetonitrile. The column was used Inertsil ODS ... Read More »

Development of New Validated Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Rosuvastatin and Aspirin in Bulk and Pharmaceutical Dosage Form

G. Gurum Jyothi, Ramesh Dhani*, V. Hari Baskar, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Rosuvastatin and Aspirin. The mobile phase consisting of 0.01N Phosphate buffer 32 as mobile phase A and ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form

B. Swathi, V. Hari Baskar*, Ramesh Dhani, M. Bharathi, M. Pavani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore– 524 346 A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformin, Pioglitazone and Glimepiride in Combined Tablet Dosage Form by using RP-HPLC

M.D. Fiaz*, Dr. R. Vani, Dr. Iffath Rizwana Post graduate student, Deccan School of Pharmacy, Hyderabad, Telangana, India. University of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Metformin, Pioglitazone and Glimepiride in Tablet dosage form by using RP-HPLC method. Methods: ... Read More »

Development and Validation of RP-HPLC Method for Simultaneous Determination of Donepezil and Memantine in their Tablet Dosage Forms

Srinivas Ganta*, Vidyadhara S Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Chowdavaram, Guntur-522018, Andhra Pradesh, India. A B S T R A C T A simple, accurate and specific RP-HPLC method has been developed and validated for the simultaneous estimation of Memantine (MEM) HCl and Donepezil (DON) HCl in bulk and pharmaceutical dosage form. Chromatographic separation was achieved on Symmetry C18 ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Glibenclamide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Ramanjaneyaulu*, Devika Subrramaniyan.G, Ramesh petchi Rajendran Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Glibenclamide in bulk and Pharmaceutical dosage form. The separation was acheived by using C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio ... Read More »

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