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Tag Archives: RP-HPLC

Antioxidant, Hepatoprotective Activity and RP-HPLC Analysis of Moringa Oleifera Pods Methanolic Extract against Alcohol Induced Hepatotoxicity

Konda Ravi Kumar, A. Prathyusha* Department of Pharmaceutical Sciences, Acharya Nagarjuna University, Guntur, Andhra Pradesh. A  B  S  T  R A C T In this study the pods of Moringa oleifera were extracted with methanol and subjected to analysis of the polyphonolic compounds by RP-HPLC method and to appraise the free radical scavenging activity and hepatoprotective activity aligned with the ... Read More »

RP-HPLC Method Development and Validation for the Simultaneous Estimation of Elbasvir and Grazoprevir Fixed dosage form

Purnacandra Rao Mendu* Department of Chemistry, Bundelkhand University, Jhansi, Uttar Pradesh, India A  B  S  T  R A C T The present research work focused on development and validation for the RP-HPLC method for the simultaneous estimation of Elbasvir and Grazoprevir in bulk and fixed dosage form. Chromatographic separation was achieved on by using Eclipse XDB -C18 (150×4.6mm, 5µm particle ... Read More »

Evaluation of Hepatoprotective Activity of Methanolic Leaf Extract of Evolvulus nummularius Linn.

G. Sindhu*, V. Jayashankar Reddy, T. Usha Kiran Reddy S V U College of Pharmaceutical Sciences, S.V University, Tirupati–517502. A B S T R A C T The present study was aimed to explore the hepatoprotecive activity in aqueous whole plant extract of EN on rats. Acute toxicity studies were conducted in Male Wistar rats by using OECD guidelines No.423. ... Read More »

A Brief Study on Steviarebaudiana–A Review

T. Usha Kiran Reddy*, R. Gouri, G. Sindhu, R. Harsha, K. Thyagaraju S V U College of Pharmaceutical Sciences, S.V University, Tirupati–517502. A B S T R A C T Stevia rebaudiana belongs to Asteraceae family and is popularly known as candy leaf. Stevia rebaudiana Bertoni is a sweet tasting medicinal herb; and has been known to contain calorie-free natural ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Darunavir and Cobicistat by RP- HPLC Method

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, T. Naga Sirisha Devi3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, ... Read More »

Novel RP-HPLC Method Development and Validation of Dasatinib and Lenvatinib in Bulk and Pharmaceutical Dosage Forms

Dr. K. Nageswara Rao1*, 2Raghava Doonaboyina, Hope Evangeline3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Trimetazidine & Propranolol in Combination by RP-HPLC

Dr. G. Uma soundarya1, Kondapu Ramya2 1Asst. Professor, Nova College of Pharmaceutical  Education & Research, Jupudi Village, Ibrahimpatnam, Krishna, Vijayawada, Andhra Pradesh, India. 2Nova College of Pharmaceutical Education & Research, Jupudi Village, Ibrahimpatnam, Krishna, Vijayawada, Andhra Pradesh, India. A B S T R A C T A new method was established for simultaneous estimation of Trimetazidine and Propranolol by RP-HPLC ... Read More »

Analytical Method Development and Validation for the Estimation of Lacidipine in Bulk and Dosage Form by RP-HPLC

Dandu Girija1*, Akkimi Padma1, A. Thirupathireddy2, B. Venkateswara reddy3 1Assistant professor, Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh       pin -523370. 2Associate Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh  pin – 523370. 3Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta (M), ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage form by RP-HPLC

N. Kalpana Devi*1, Tirupathi Rao Velamala2, D.S.S.N.Neelima3 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Sulphadoxine and Pyrimethamine, in its pure form as well as in ... Read More »

Stability indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Metformin and Teneligliptin in Pharmaceutical Formulation

Ramesh Dhani*, V. Haribaskar, J. Priyanka Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Teneligliptin in pharmaceutical dosage form. Chromatogram was run through ODS2 C 18 (4.6 x 200mm, 10.0µm)column.   Mobile phase containing ... Read More »

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