Tuesday , 25 July 2017

Tag Archives: RP-HPLC

Method Development and Validation of Metformin in Pure and Its Tablet Dosage Form by using RP-HPLC

Dr. Hareesh Dara, Meesa Rajendar, Dr. D Siva Dinesh St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T High Performance Liquid Chromatography is now one of the most powerful tools in analytical chemistry. It has the ability to separate, identify, and quantitative the compounds that are present in any sample that can ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Method Development and Validation of Olodaterol and Tiotropium by RP-HPLC Method

Farhana Shaheen*, Salma Begum, Rubina Kauser, Airaj Mahajabeen, MD Muzammil Hassan MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reverse phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Cilnidipine and Telmisartan in Combined Tablet Dosage Form by Using RP-HPLC

R. Chandra Sekhar*, Prof. Ravindernath Post graduate student, University College of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Cilnidipine and Telmisartan in Tablet dosage form by using RP-HPLC method. Methods: The chromatographic separation was performed on ZORBAX SB-PHENYL, 250X 4.6mm. ... Read More »

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

Method Development and Validation of Artemether and Lumifantrine by RP-HPLC

Farhana Shaheen*, Rubina Kauser, Salma Begum, Airaj Mahajabeen, Md Fasiuddin MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Introduction Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the immobilized ... Read More »

Method Development and Validation of Paracetamol, Guaifenesin, Ambroxol Hydrochloride, Phenylephrine Hydrochloride and Chlorpheniramine Maleate in Bulk and Combined Dosage Form Using RP-HPLC Technique

Swapnil B. Deshmukh*, Vilas L Badgujar, Priyanka N Chhajed, Trupti C. Mahajan, Tanvirahmad J. Shaikh DCS’S A.R.A College of Pharmacy, Nagaon, Dhule A B S T R A C T An RP-HPLC method for the simultaneous determination of Paracetamol, Guaifenesin, Ambroxol hydrochloride, Phenylephrine hydrochloride and Chlorpheniramine maleate in tablets was developed and validated ® as per ICH and FDA guidelines. ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril and Hydrochlorothiazide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Jyothi Keerthi*, G. Devika Subramaniyan, Ramesh Petchi, Rajendran Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A Reverse Phase High Performance Liquid Chromatography method was developed for the determination of Enalapril and Hydrochlorothiazide in bulk and Pharmaceutical dosage form. The separation was achieved on an Inertsil ODS (250×4.6mm),5µm column by using a ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Ivacaftor and Lumacaftor in its Bulk and Pharmaceutical Dosage Forms

Satheesh1, Dr. D. Naresh2, P.Sowjanya3, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Ivacaftor and Lumacaftor by RP-HPLC method.  ... Read More »

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