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Tag Archives: quinazoline

Quinazoline Derivatives and its Biological Significance–A Review

V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha3, K. Hari Nagamaddaiah2 1, 2Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, Andhra Pradesh, India. 3Department of Bio-technology, Sri Krishnadevaraya University College of Engineering and Technology, S.K. University, Anantapuramu–515003, Andhra Pradesh, India. A B S T R A C T Medicinal chemistry is concerned with discovery, development, synthesis in laboratory, thousands of ... Read More »

Synthesis, Characterisation and Biological Evaluation of Novel Di substituted Quinazoline Linked with Cis Substituted Thio morpholine and 1, 2, 4 Triazole Moieties

V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, Andhra Pradesh, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, Andhra Pradesh, India. A B S T R A C T A series of Quinazoline derivatives11 (a-f) were prepared by Nucleophilic substitution reaction of 2,4 di chloro ... Read More »

A Computational Network Model of Protein Kinases for Cell Survival/Death and its congruent tanner circuit

Rose Mary Simon, Md. Afroz Alam*  Department of bioinformatics, Karunya University, Karunya Nagar, Coimbatore-641114, Tamil Nadu, India Abstract Computational modeling is useful as a means to assemble and test what we know about proteins and networks. The network model of EGFR pathway for cell survival/death has been implemented using SPICE simulator and Matlab. The sub pathways in EGFR pathways have ... Read More »

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