Wednesday , 21 February 2018


Method Development and Validation of Paracetamol, Guaifenesin, Ambroxol Hydrochloride, Phenylephrine Hydrochloride and Chlorpheniramine Maleate in Bulk and Combined Dosage Form Using RP-HPLC Technique

Swapnil B. Deshmukh*, Vilas L Badgujar, Priyanka N Chhajed, Trupti C. Mahajan, Tanvirahmad J. Shaikh DCS’S A.R.A College of Pharmacy, Nagaon, Dhule A B S T R A C T An RP-HPLC method for the simultaneous determination of Paracetamol, Guaifenesin, Ambroxol hydrochloride, Phenylephrine hydrochloride and Chlorpheniramine maleate in tablets was developed and validated ® as per ICH and FDA guidelines. ... Read More »

Electrochemical Quantification of Paracetamol in Locally Available Pain-Killer Drug Formulaions, Using Cobalt Hexacyano Ferrate Based Carbon Paste Sensor, Voltammetrically

R. C. Saini1*, Letemariam Gebresilassie2, Tadele Hunde1, Mekonen Tirfu1, Rishi pal3 1Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, P.O. Box -231, Mekelle, Ethiopia. 2Department of Chemistry, Mizan Tepi University, P.O. Box -Mizan, Ethiopia. 3SBMN Institute of Pharma Sciences and Research, Baba Mastnath University, Asthal Bohr -124021, Haryana, India. A B S T R A C T Paracetamol, ... Read More »

Hepatoprotective Activity of Methanolic Extract of Barleria Montana Nees Leaves in Paracetamol Induced Rat Hepatic Injury

Gunji Venkateswarlu*1, G. Swarupa Rani2, M. Vani3, Naga Prashant. K4 1*Assistant Prof, Department of Pharmacognosy, Narasaraopeta Institute of Pharmaceutical sciences, Narasaraopet, Guntur, Andhra Pradesh, India. 2Assistant Prof, Department of Pharmacology, Narasaraopeta Institute of Pharmaceutical sciences, Narasaraopet, Guntur, Andhra Pradesh, India. 3Asst. Professor, Department of Pharmacognosy, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Andhra Pradesh, India. 4Assistant Prof, Department of Pharmaceutical Chemistry, ... Read More »

Hepatoprotective Activity of Ethanolic Extract of Rhizomes of Curculigo Orchioides

D. Bargavi*, Anupam Kanti Bag, Sk. Karimulla, M. Gobinath Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. A B S T R A C T Hepatotoxicity in one of the major parameters need to be consider in drug therapy, because most of the drugs in single at low/high doses for a prolonged period or multiple ... Read More »

Method Development and Validation for Simultaneous Determination a Multiple Drug Dosage Form of Paracetamol, Phenylepherine and Caffeine by RP-HPLC

Dr. Samson Israel Deta*1, Dr. Kommana Balaram Kumar2, Hayelom G/Kirstos Mangesha3 1Asst. Prof, Adigrat University, Ethiopia 2Asst.Prof, University of Gondar, Ethiopia 3Lecturer, Adigrat University, Ethiopia A B S T R A C T This method describes a procedure to quantify the assay of Paracetamol, Phenylepherine and caffeine tablet using a mobile phase containing containing mixture of 880 mL of sodium ... Read More »

Analytical Method Development and Validation of Simultaneous Estimation of Tramadol, Paracetamol, Domperidone in Tablet Dosage Form by RP-HPLC

Nagaraju.Y*, A. Ajitha and Uma Maheshwar Rao. V Departmentof Pharmaceutical Analysis, CMR College of Pharmacy, Ranga Reddy-501401, India A B S T R A C T A simple reverse phase high pressure liquid chromatography (RP-HPLC) method has been developed and validated for simultaneous estimation of tramadol paracetamol and domperidone in tablet dosage forms. The compounds were separated on inertsil C-18 ... Read More »

Formulation and Evaluation of Transdermal Patches Containing Paracetamol

Author Details Navneet Kumar Verma*1, Anubha Gupta1, Harendra Prasad2, Vikash Chandra3 1Department of Pharmacy, Rameshwaram Institute of Technology and Management Lucknow (U.P), India 2Faculty of B. Pharmacy, CSM Group of Institution, Allahabad, (U.P), India 3Dr. M.C.Saxena College of Pharmacy, Lucknow (U.P), India Abstract It is the most important part of Pharmaceutical dosage forms; Transdermal Drug Delivery System (TDDS) established itself ... Read More »

Isolation, Chracterization of Caralluma adscendens [Roxb] and Its Biological Evaluation

About author : P. Jaya Preethi*, S. Ruby Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, TamilNadu, India. *E-mail: Abstract: Caralluma adscendens Roxb a genus of the family Asclepiadaceae is an important medicinal and widely distributed succulent plant found in dry regions of world. The present paper deals with invitro anti cancer and hepatoprotective activities ... Read More »


About author: Navneet Kumar Verma* Department of Pharmacy, Rameshwaram Institute of Technology and Management Lucknow (U.P), India *e-mail- ABSTRACT: The objective of the study is to evaluate ethylcellulose as a coat for controlled release microcapsules of paracetamol. Ethylcellulose coated microcapsules were prepared by an emulsion-solvent evaporation method employing different proportions of core and coat and the microcapsules were evaluated ... Read More »

Clinical Pharmacology and therapeutics

Clinical Pharmacology and therapeutics JAMES M RITTER LIONEL D LEWIS TIMOTHY GK MANT ALBERT FERRO Clinical pharmacology is the science of drug use in humans. Clinicians of all specialties prescribe drugs on a daily basis, and this is both one of the most useful but also one of the most dangerous activities of our professional lives. Understanding the principles of ... Read More »

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