Thursday , 18 July 2019

Tag Archives: N-alkylation

Synthesis of the new carboxylic α,α-diamino acid: Benzoylamino-(2-methyl-quinolin-4-ylamino) acetic acid

El Houssine Mabrouk* Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco A B S T R A C T After the obtaining of the N-protected methyl α,α-diamino ester via N-alkylation reaction between methyl α-bromo glycinate N-benzoylated and 2-methyl quinolin-4-amine, the synthesis of benzoylamino-(2-methyl-quinolin-4-ylamino) acetic acid in high yield through ... Read More »

Synthesis of the new carboxylic α,α-diamino ester: Methyl 2-benzamido-2-(N-benzyl N-methylamino)acetate

El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of  Sciences Dhar El  Mahraz, University  Sidi  Mohamed Ben  Abdellah,  B.P. 1796,  Fez,  Morocco  A B S T R A C T The title compound, Methyl 2-benzamido-2-(N-benzyl N-methylamino) acetate was synthesized in high yield by N-alkylation reaction between methyl α-bromo glycinate or methyl α-azido glycinate N-benzoylated and N-benzyl-N-methylamine ... Read More »

Synthesis of N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide

El Houssine Mabrouk1 1Laboratory of Organic Chemistry, Faculty of Sciences DharElMehraz, University Sidi Mohamed Ben Abdellah, Fez, B.P.:1796-Fès Atlas, Morocco ABSTRACT The title compound, N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide2, was synthesized in high yield, via N-alkylation reaction of methyl 2-azido-2-benzamidoacetate or methyl 2-bromo-2-benzamidoacetate with o-phenylenediaminein acetone, with the presence of diisopropylethylamine(DIEPA) as a base. The structure of the prepared compound was characterized by 1H, ... Read More »

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