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El Houssine Mabrouk*1 and Abdelilah El Hallaoui2 1Engineering, Electrochemistry, Modelling & Environmental Laboratory (LIEME), Department of Chemistry, Faculty of sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco. 2Department of Chemistry, Faculty of Sciences and Technics, BP 509 Boutalamine, Errachidia, Moulay Ismail University Meknes, Morocco. A B S T R A C T 2-[(Benzoylamino carboxymethyl) amino] ... Read More »
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Tag Archives: N-alkylation
Synthesis of the new carboxylic α,α-diamino acid: Benzoylamino-(2-methyl-quinolin-4-ylamino) acetic acid
El Houssine Mabrouk* Laboratory of Organic Chemistry, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco A B S T R A C T After the obtaining of the N-protected methyl α,α-diamino ester via N-alkylation reaction between methyl α-bromo glycinate N-benzoylated and 2-methyl quinolin-4-amine, the synthesis of benzoylamino-(2-methyl-quinolin-4-ylamino) acetic acid in high yield through ... Read More »
Synthesis of the new carboxylic α,α-diamino ester: Methyl 2-benzamido-2-(N-benzyl N-methylamino)acetate
El Houssine Mabrouk and Abdelilah El Hallaoui Laboratory of Organic Chemistry, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, B.P. 1796, Fez, Morocco A B S T R A C T The title compound, Methyl 2-benzamido-2-(N-benzyl N-methylamino) acetate was synthesized in high yield by N-alkylation reaction between methyl α-bromo glycinate or methyl α-azido glycinate N-benzoylated and N-benzyl-N-methylamine ... Read More »
Synthesis of N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide
El Houssine Mabrouk1 1Laboratory of Organic Chemistry, Faculty of Sciences DharElMehraz, University Sidi Mohamed Ben Abdellah, Fez, B.P.:1796-Fès Atlas, Morocco ABSTRACT The title compound, N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide2, was synthesized in high yield, via N-alkylation reaction of methyl 2-azido-2-benzamidoacetate or methyl 2-bromo-2-benzamidoacetate with o-phenylenediaminein acetone, with the presence of diisopropylethylamine(DIEPA) as a base. The structure of the prepared compound was characterized by 1H, ... Read More »
