Friday , 6 December 2019

Tag Archives: Microspheres

Formulation and Evaluation of Microspheres of Aceclofenac

Murugan Mounika1, Nallapu Prathyusha Evangelin2, Nomula Chaitanya3, B. Prabhakar Reddy*4 1,2,3Vignan Institute of Pharmaceutical Sciences, Vignan Hills, Deshmukhi, Yadadri, Bhongir, Telangana, India. 4Associate Professor, Department of Pharmaceutics, Vignan Institute of Pharmaceutical Sciences, Vignan Hills, Deshmukhi, Yadadri, Bhongir, Telangana, India. A B S T R A C T In the present work, Aceclofenac microspheres using HPMC K 4 M., Eudragit L100, Eudragit ... Read More »

Formulation and Evaluation of Ziprasidone Microspheres by Sovlent Evaporation Method

Kodur Sumathi, Penabaka Venugopalaiah*, Yerikala Ramesh Department of Pharmaceutics, Ratanam Institute of Pharmacy, Nellore -524 346, Andhra Pradesh, India A B S T R A C T The objective of the present study was formulation and evaluation of Ziprasidone microspheres by using solvent evaporation technique. Ziprasidone is loaded with ethyl cellulose & HPMC 15 microspheres and it was prepared by ... Read More »

Glipizide Microspheres: In-Vitro Characterization

Padmaja D, Hindustan Abdul Ahad, Shahin Farhana S, Sravani A, FaheemB Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India A B S T R A C T The main aim of present investigation is to determine best grade of HPMC among HPMC K4M, HPMC K15M and HPMC K100M for preparing floating microspheres. The drug excipient compatibility was checked by DSC ... Read More »

Formulation Development and In-vitro Evaluation of Valacyclovir Bioadhesive Microspheres

Ch. Srilatha*1, P. Prvallika Reddy1, Dr. M. Ravi Kumar1, Dr. K. Someshwar2 1Geetanjali College of Pharmacy, Keesara, Rangareddy, Telangana, India 2Manager, Formulation R&D, Karthikeya Drugs and Pharmaceuticals Private Limited, Kothapet, Hyderabad. A B S T R A C T In the present work, bioadhesive microspheres of Valacyclovir using Sodium alginate along with Carbopol 934, Carbopol 971, HPMC  K4M as copolymers were formulated ... Read More »

Formulation and In-Vitro Evaluation of Doxorubicin Microspheres for the Treatment of Lymphoblastic Leukemia

Kondru Lalitha*, Beedha Saraswathi Mother Teresa Pharmacy College, Kothuru, Sathupally- 507303, Khammam, Telangana, India A B S T R A C T In the present work, bioadhesive microspheres of Doxorubicin using Sodium alginate along with Carbopol 934, Carbopol 971, HPMC  K4M as copolymers were formulated to deliver Doxorubicin via oral route. The results of this investigation indicate that ionic cross linking technique Ionotropic gelation ... Read More »

Design, Characterization and Evaluation of Cefaclor Microspheres by Solvent Evaporation Method

Mallikarjun V.1*, Sriharsha S.N.1, D. Yashwanth Kumar2 1Pacific College of Pharmacy, Pacific University, Udaipur, Rajasthan, India 2Scientific and Applied Research Center, Hyderabad, Telangana, India. A B S T R A C T The aim of the present study was to develop and characterize cefaclor microspheres containing ethyl cellulose as a sustained release delivery system. Cefaclor microspheres are prepared by solvent ... Read More »

Formulation and Evaluation of Cefixime Loaded Microspheres for Extended Delivery

Mallikarjun Vasam*1, Dr. S.N. Sri Harsha1, P. Hyma2, D. Yashwanth Kumar2 1Pacific University, Udaipur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, India A B S T R A C T Microspheres of cefixime were prepared using the solvent evaporation method. The effect of different factor such as concentration of ethyl cellulose (polymer) on the characteristics of the microspheres ... Read More »

Formulation and evaluation of Controlled Release Microspheres of Zolpidem Tartrate

Nimish.S*1, Dr. S.N. Sri Harsha2, K.S.S.N. Neelima2, D. Yashwanth Kumar2 1Dr. K.N. Modi University, Jaipur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, India A B S T R A C T Microspheres of Zolpidem tartrate were prepared using the non-aqueous emulsification solvent evaporation method. The impacts of different factors such as stirring rate, concentration of acrycoat S 100 ... Read More »

Pharmacokinetic Evaluation of Eudragit® Microspheres of Cefdinir

Mallikarjun Vasam*1,Dr. S.N. Sri Harsha2, K.S.S.N. Neelima2, D. Yashwanth Kumar2 1Pacific University, Udaipur, Rajasthan, India 2SARC (Scientific and Applied Research Center), Hyderabad, India A B S T R A C T The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water-soluble drug, cefdinir, using Copolymers synthesized from acrylic and methacrylic acid esters ... Read More »

Preparation and Evaluation Glutaraldehyde Cross Linked sodium alginate Microspheres Containing Rivastigmine Tartrate

Nimish.S*1, Dr. S.N. Sri Harsha1, P. Hyma2, D. Yashwanth Kumar2 1Department ofPharmaceutics, Dr. K.N. Modi University, Jaipur, India 2SARC (Scientific and Applied Research Center), Hyderabad, India A B S T R A C T Rivastigmine tartrate is an anticholine esterase inhibitor that used in the treatment of Alzheimer’s disease. In this study an attempt was made to encapsulate the Rivastigmine ... Read More »

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