Tuesday , 22 October 2019

Tag Archives: metformin

Formulation and Evaluation of Metformin Hydrochloride and Linagliptin Immediate Release Tablets

P. Ramya*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India-518218 A B S T R A C T The main objective of the work is to design and develop immediate release  tablets of Metformin Hydrochloride  and Linagliptin  in combination using different granulating agents and to perform suitable studies for the development ... Read More »

Stability indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Metformin and Teneligliptin in Pharmaceutical Formulation

Ramesh Dhani*, V. Haribaskar, J. Priyanka Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Teneligliptin in pharmaceutical dosage form. Chromatogram was run through ODS2 C 18 (4.6 x 200mm, 10.0µm)column.   Mobile phase containing ... Read More »

Formulation and Evaluation of Floating and Mucoadhesive Tablet of Oral Hypoglycemic Drug Metformin

G. Jagadish*1, Dr. Anil Kumar Middha*2 1Research Scholar Department of Pharmaceuttics, OPJS University, Churu, Rajasthan 2 Dr. Anil Kumar Middha, OPJS University, Churu, Rajasthan ABSTRACT In the present research work gastro retentive mucoadhesive floating formulation of Metformin by using various hydrophilic polymers. Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformin, Pioglitazone and Glimepiride in Combined Tablet Dosage Form by using RP-HPLC

M.D. Fiaz*, Dr. R. Vani, Dr. Iffath Rizwana Post graduate student, Deccan School of Pharmacy, Hyderabad, Telangana, India. University of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Metformin, Pioglitazone and Glimepiride in Tablet dosage form by using RP-HPLC method. Methods: ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Glibenclamide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Ramanjaneyaulu*, Devika Subrramaniyan.G, Ramesh petchi Rajendran Bomma Institute of Pharmacy, Khammam, Telangana, India A B S T R A C T A reverse phase high performance liquid chromatographic method was developed for the determination of Metformin and Glibenclamide in bulk and Pharmaceutical dosage form. The separation was acheived by using C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio ... Read More »

Method Development and Validation of Metformin in Pure and Its Tablet Dosage Form by using RP-HPLC

Dr. Hareesh Dara, Meesa Rajendar, Dr. D Siva Dinesh St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T High Performance Liquid Chromatography is now one of the most powerful tools in analytical chemistry. It has the ability to separate, identify, and quantitative the compounds that are present in any sample that can ... Read More »

In Vitro Anti-Diabetic and Anti-Arthritic Activity of Hydro Ethanolic Extract of Cynodon Dactylon

K. Jyothsna Jayaraju*, Y. Meenakshi, R. Renuka Devi, P. Sravani, K. Murali Krishna, R. Leela Dr. K.V. Subba Reddy Institute of Pharmacy, Dupadu, Kurnool-518218, Andhra Pradesh, India A B S T R A C T Objective: The present study is aimed to evaluate the in-vitro anti-diabetic and anti-arthritic activity of hydro ethanolic extract of whole plant of Cynodon dactylon. Methods: ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformin and Vildagliptin by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Punna Venkateshwarlu*, CH. Shankar Department of Pharmaceutical Analysis, Vikas College of Pharmaceutical Sciences, Rayanigudem, Suryapet, Nalgonda, Telangana, India-508376 A B S T R A C T The chromatographic conditions were successfully developed for the separation of Metformin and Vildagliptin by using C18 Column (150 mm x 4.6 mm) 5 µm, flow rate was 1ml/min, mobile phase ratio was Methanol: Phosphate ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Metformine and Gemigliptin by RP-HPLC Method

Nair Ayana Ramesh1, Dr. D. Naresh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The estimation of metformin and gemigliptin was done by RP-HPLC. The Phosphate buffer was ... Read More »

Analytical Method Development and Validation for Elbasvir and Grazoprevir in Combine Phaarmaceutical Dosage forms by RP-HPLC

Abilash Reddy Vancha1, Dr. D. Naresh1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T HPLC is at present one of the most sophisticated tool of the ... Read More »

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