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Tag Archives: Leukemia

Thiopurine methyl transferase enzyme activity-relationship to the dose and adverse effects of 6-mercaptopurine in children with acute lymphoblastic leukemia

Osama A.E. Ali*, Nabeel A.J.Ali1, Janan G. Hassan2 1MBChB, PhD, Department of Pharmacology, College of Medicine, University of Basrah, Basrah, Iraq 2MBChB,FICMS, Department of Pediatrics, College of Medicine, University of Basrah, Basrah, Iraq A B S T R A C T Background: There are genetic variations in the activity of the enzyme thiopurine methyl transferase (TPMT) which lead to differences ... Read More »

Synthesis and Spectral Studies of Novel 3-(5-mercapto-1, 3, 4-oxadiazol-2-yl)-2H-chromen-2-one Derivatives as Anticancer Agents

Chamandeep Kaur Bhinder1*, Amandeep Kaur2 1Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India 2Department of Pharmaceutical Chemistry, ASBASJSM COP, Bela, Punjab-140111, India A B S T R A C T In recent years, researchers hunt for a novel anticancer agent mainly from plants. Among various phytochemicals, coumarins have attracted considerable interest in the past few years due to their ... Read More »

A Review on Myeloproliferative disorder

K.B. Kotade*1, P.Kadbhane1, S.B Somwanshi2, K.B.Dhamak3 1Department of Pharmacology, P.R.E.S.’s, College of Pharmacy (For Women), Chincholi, Nashik-422 102. 2Department of Pharmaceutics, P.R.E.S.’s, College of Pharmacy (For Women), Chincholi, Nashik-422 102. 3Department of Pharmaceutical Chemistry, P.R.E.S.’s, College of Pharmacy (For Women), Chincholi, Nashik-422 102 A B S T R A C T The term myeloproliferative disorder (MPD) was first introduced by ... Read More »

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