Saturday , 21 September 2019

Tag Archives: ICH guidelines

Review on Analytical Method Validation Procedures

k. Surendra*, SK. Karishma, G. Obulesu, M. Naveena Rao’s College of Pharmacy, Chemudugunta, Venkatachalam, Nellore, Andhra Pradesh-524320 A B S T R A C T Pharmaceutical analysis plays a very prominent role in quality assurance as well as quality control of bulk drugs and pharmaceutical formulations, of which analytical method development & validation is the basic activity. Analytical techniques are ... Read More »

A Novel RP-HPLC Method Development and Validation for the Estimation of Pyrimethamine in Bulk and its Pharmaceutical Formulation

U. Srinivasulu*1, N. Devanna2, A. Sandhya 3, B. Siva Sai Kiran3, S. Muneer3 1Associate Professor of Chemistry, SBSYM Degree College, Kurnool-518004, A.P., India 2Professor and Director, Department of Chemistry, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India. 3Department of Pharmaceutical Sciences, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India A B S T R A C T A simple, ... Read More »

A Simple Analytical Method Development and Validation for the Quantification of Darifenacin Hydrobromide in Pure and Its Tablet Dosage Form using UV-Spectrophotometry

A. Lakshmi Bhagya Sree*, B. Siva Sai Kiran, S. Muneer, K.B Chandra Sekhar Department of Pharmaceutical Analysis, JNTUA- Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515001, A.P, India. A B S T R A C T A simple, accurate and precise Zero order spectroscopy method was developed and validated for the estimation of Darifenacin Hbr bulk and pharmaceutical dosage forms.  Distilled ... Read More »

Method Development and Validation of Mycophenolate Mofetil by RP-HPLC

Rubina Kauser, M. Mushraff Ali Khan, Airaj Mahajabeen, Farhana Shaheen, Salma Begum MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »

A New Validated Stability indicating RP-HPLC Method for the Quantitative Analysis of Phentermine Hydrochloride in Tablet Dosage Form

K.V. Lalitha*1, R. Kiranjyothi2 1Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research, Ananthapuramu – 515001, Andhra Pradesh, India. 2Department of Pharmaceutical Analysis, JNTUA – Oil Technological Research Institute, Ananthapuramu – 515001, Andhra Pradesh, India. A B S T R A C T A novel stability indicating RP-HPLC method was developed for the estimation of Phentermine hydrochloride in ... Read More »

Analytical Method Development and Validation for the Estimation of Efavirenz by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Gobala Krishnan P*1, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy & Research centre, Nellore, Andhra Pradesh, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Efavirenz  by using KromosilColumn (100-5 C18.60×4.6mm), flow rate was 1ml/min, mobile phase ratio was Acetonitril: Phosphate buffer PH ... Read More »

Development and Validation of New UV Spectroscopic and HPLC Methods for the Estimation of Zidovudine in Bulk and Pharmaceutical Dosage Form

Telugu Naga Mohan, Shaik Mohammed Yusuf*, Seerla Eswaraiah, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical sciences, Proddatur, YSR Kadapa [Dist]. AP. India.  A B S T R A C T In the present work, two simple, sensitive and specific methods (UV Spectroscopy and RP-HPLC) have been developed for the quantitative estimation of Zidovudine in bulk and pharmaceutical ... Read More »

UV Spectroscopic Method for Estimation of Enalapril Maleate in Bulk and in its Tablets

UV Spectroscopic Method for Estimation of Enalapril Maleate in Bulk and in its Tablets B. Mohammed Ishaq*, S. Muneer, S. Praveena, B. Famida, Hindustan Abdul Ahad Department of Pharmaceutical Analysis, Balaji College of Pharmacy, Anantapur, AP, India. A B S T R A C T A simple, rapid and sensitive UV spectrophotometric method was developed for the estimation of Enalapril ... Read More »

A Simple UV Spectroscopic Method for the Determination of Tramadol HCl in Bulk and It’s Dosage Form

B. Famida*, S. Muneer, B. Mohammed Ishaq, Hindustan Abdul Ahad, T. Nuzhath PG Department of Pharmaceutical Analysis, Balaji College of pharmacy, Ananthapuramu, Andhra Pradesh, India A B S T R A C T Tramadol hydrochloride (TDL), is chemically [2-(dimethyl amino methyl)-1-(3-methoxyphenyl) cyclohexanol]. [1] It is a centrally acting analgesic, used for treating moderate to severepain, possesses agonist actions at the ... Read More »

Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Moxifloxacin and Prednisolone in Bulk Drug and Pharmaceutical Dosage

K. Kalyani2, P. Sowjanya3, Dr. T. Rajesh4, Dr. Gampa Vijaya Kumar*1 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. 2,3,4Deapartment of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy. A B S T R A C T A simple, specific, and fast stability indicating reverse phase liquid chromatographic method was established ... Read More »

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