Friday , 25 September 2020

Tag Archives: Forced Degradation

Novel validated reverse-phase chromatographic method for the stability-indicating studies of Tofacitinib dosage form

Birhanu Motbaynor* Haramaya University, College of Health and Medical Sciences, School of Pharmacy, Department of Pharmaceutical Chemistry, Harar, Ethiopia A  B  S  T  R A C T The objective of the current study was to develop and validate a rapid, precise, specific and stability-indicating reverse phase HPLC for the quantitative determination of TOFACITINIB in its dosage form. The determination is ... Read More »

Analytical Method Development and Validation for the Estimation of Brivaracetam in Bulk and Its Dosage Form by RP-HPLC

Patta Salomi*, S. Rama Thulasi, K. Ravindra Reddy P. Rami Reddy Memorial College of Pharmacy, Kadapa-516003, Andhra Pradesh, India ABSTRACT A simple reverse phase liquid Chromatographic method has been developed and subsequently validated for determination of Brivaracetam. The mobile composition of Potassium Dihydrogen orthophosphate (0.02M): Methanol 40:60v/v Buffer pH 6.0 adjusted with ortho phosphoric acid, waters column of C18 (250X4.6 ... Read More »

A Novel Validated Stability Indacating Method for Simultaneous Estimation of Emtricitabine, Tenofovir and Efavirenz in Tablet Dosage Form by RP-HPLC

Kommana Balaram Kumar*, Yohanes Ayele, Birhanu Motbatnor aAssistant Professor, Department of Pharmaceutical analysis and Quality Assurance School of Pharmacy, Haramaya University, Ethiopia. bDepartment of clinical pharmacy, H.O.D, School of pharmacy, Haramaya University, Ethiopia cLecturer, Department of pharmaceutical analysis and quality assurance School of pharmacy, Haramaya University, Ethiopia A  B  S  T  R A C T The objective of the current study ... Read More »

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

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