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Tag Archives: bioavailability

A Review on Innovative Formulation Approach to Enhance Occular Bioavailability

Harendra Prasad*1 and Navneet Kumar Verma2 1Chhatrapati Shahuji Maharaj Group of Institution Faculty of B.Pharmacy, Allahabad U.P., India 2Rameshwaram Institute of Technology and Management Lucknow, U.P, India Received: 14 June 2014, Accepted: 19 July 2014, Published Online: 10 August 2014 Abstract Conventional eye drops shows relatively low bioavailability due to poor precorneal contact time. In situ hydrogel are of great ... Read More »

Solubility Enhancement Techniques and Use of Dendrimers in the Solubilization of Water Insoluble and Poorly Soluble Drugs-A Review

Navneet Kumar Verma*1, Anubha Gupta1, Harendra Prasad2, Asha Roshan3, Shobhit Prakash Srivastava4, Vikash Chandra4  1Department of Pharmacy, Rameshwaram Institute of Technology and Management, Lucknow, (U.P), India 2Faculty of B. Pharmacy, CSM Group of Institution, Allahabad, (U.P), India 3R.K. College of Pharmacy, Azamgarh, (U.P), India 4Dr. M.C. Saxena College of Pharmacy, Lucknow, (U.P), India Received: 6 May 2014, Accepted: 12 June ... Read More »

Method used for Solubility Enhancement of Poorly water Soluble Drug-A Review

About author Prasad Harendra*, Verma Navneet Kumar Rameshwaram Institute of technology and Management Lucknow, U.P. India E-mail: [email protected] Abstract The slow dissolution rate exhibited by poorly water-soluble drugs is a major challenge in the drug development process. Following oral administration, drugs with slow dissolution rates generally show erratic and incomplete absorption which may lead to therapeutic failure. The aim of ... Read More »

DissoCubes: A Novel Formulation to Enhance Solubility

About author S.S Siddheshwar*, S.B. Somwanshi, R.T. Dolas, A.N. Merekar, R.K. Godge, S. R. Pattan Department of Pharmaceutics, P.R.E.S.’s, Pravara Rural College of Pharmacy, Loni. Department of Pharmaceutical Chemistry, P.R.E.S.’s, Pravara Rural College of Pharmacy, Loni. E-mail: [email protected] Abstract Most of drugs are poorly soluble and have bioavailability problems. Therefore, there is an urgent need to find solutions for the ... Read More »

Design and Evaluation of Extended release Multiunit Particulate System for Novel class-I Antidepressant Drug

Author Details Ravi Parekh*, Tiwari Ajaykumar, Dr. B.S. Srivastav Deparment of Pharmaceutical science Jaipur National University, SADTM Campus, Jaipur-302025 *E-mail: [email protected] ABSTRACT Pellets have long been employed to improve the bioavailability of drugs undergoing significant first pass hepatic metabolism. Venlafaxine hcl is an antidepressant drug. It has very strong side effect of vomiting in the IR dosage form, so it ... Read More »

A NOVEL REVIEW ON NATURAL POLYMERS USED IN FORMULATION OF PHARMACEUTICAL DOSAGE FORMS

ABOUT AUTHOR D. Mahidhar Reddy*, Sk. Razia Begum,K. Jyothirmai, G.V. Dileep Kumar, S. Jayasree, J. Jeevankumar, A.V.S. Gita Samira Department of Pharmaceutics, Narayana Pharmacy College, Chinthareddy palem,Nellore,A.P,India- 524004 Sri Padmavathi School of Pharmacy,Thirupathi, Chitoor (dist), A.P, India – 517503 E-mail:  [email protected], [email protected] ABSTRACT All pharmaceutical dosage forms contain many additives besides the active ingredients to assist manufacturing and to obtain the ... Read More »

Design and Evaluation of Extended release Multiunit Particulate System for Novel class1 Antidepressant Drug

ABOUT AUTHOR Ravi parekh*, Tiwari Ajaykumar, Dr.B.S. Srivastav Deparment of Pharmaceutical science, Jaipur National University, SADTM Campus, Jaipur-302025, India [email protected] ABSTRACT Pellets have long been employed to improve the bioavailability of drugs undergoing significant first pass hepatic metabolism. Venlafaxine Hcl is an antidepressant drug. It has very strong side effect of vomiting in the IR dosage form, so it is ... Read More »

Biodegradable Polymeric Nanoparticles: Drug Delivery Systems-A Review

Author Details Bhavani.B*, Mohan.K, J. Vijaya Ratna A.U.College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, AP, India E-mail: [email protected] Abstract Biodegradable nanoparticles have been used frequently as drug delivery vehicles due to its grand bioavailability, better encapsulation, control release and less toxic properties. Various nanoparticulate systems, general synthesis and encapsulation process, control release and improvement of therapeutic value of nanoencapsulated drugs ... Read More »

FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLET OF TAPENTADOL

ABOUT AUTHOR Asija Rajesh*, Rathi Harish, Asija Sangeeta Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, India. Email: [email protected], [email protected] ABSTRACT The objective of the present study was to develop sustained release tablets of Tapentadol (250mg) by wet granulation using various grades of hydrophilic polymer like Hydroxy propyl methyl cellulose K100M and Hydroxy propyl methyl cellulose 5cps or ... Read More »

PowderJect Device: A needle free tool for transdermal drug delivery

About author : S.S Siddheshwar*, M. R. Shiradkar, S.B. Somwanshi, R.T. Dolas, A.N. Merekar, S. R. Pattan Dept. of  Pharmacy, Acharya Nagarjuna University, Guntur (A.P), India *e-mail: [email protected] Introduction The major drawback of drug administered subcutaneously is its invasiveness, which leads to pain and discomfort to the patients. Drug delivery using patches and diffusion through the skin has the merit of being ... Read More »

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