Monday , 24 February 2020

Tag Archives: anticancer

A Review on Imidazole Pharmacological Activities

Pooja Kumari* Department of pharmaceutical chemistry, Rajiv Academy for Pharmacy, N.H. #2, Mathura Delhi Road, P.O. CHHATIKARA, Mathura, Uttar Pradesh (INDIA) 281001 A B S T R A C T Imidazole is a heterocyclic compound which contains the ring with the 2 atom of nitrogen in the1 and 3 position of the cycle. Imidazole derivatives which have shown biological activity ... Read More »

Role of Medicinal Plants in Cancer Treatment- A Review

Andalamala Venkata Ramanamma*, Mamuduru Penchala Vijaykumar, Dr. P. Venkatesh Jagan’s College of Pharmacy, Jangala Kandriga, Muthukur, SPSR Nellore-524348. A B S T R A C T India is a peninsula of herbal hub, in which Siddha system of medicine has flourished as an enlightment in the field of Medicine. Currently medicinal plants have become the paramount source of drug discovery ... Read More »

SAR Study, Molecular Property and In Silico study of Novel Tetrahydroquinolines bearing Trifluoromethyl Group for Anticancer, Antimalarial, Anti HIV Activities

PS Pradeep, NM Jagadeesh, HC Kiran Kumar, KM Mahadevan* Department of Post Graduate Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, P. G. Centre, Kadur, Karnataka-577 548, India. A B S T R A C T A milder and efficient method was described for the synthesis of cis-1-(2-(4-(trifluoromethyl) phenyl)-1, 2, 3, 4-tetrahydroquinolin-4-yl) pyrrolidin-2-ones/azepan-2-ones (3a-d, 4a-d) via imino Diels-Alder ... Read More »

SAR Study, Molecular Property and In Silico study of Novel Tetrahydroquinolines bearing Trifluoromethyl Group for Anticancer, Antimalarial, Anti HIV Activities

PS Pradeep, NM Jagadeesh, HC Kiran Kumar, KM Mahadevan* Department of Post Graduate Studies and Research in Chemistry, School of Chemical Sciences, Kuvempu University, P. G. Centre, Kadur, Karnataka-577 548, India. A B S T R A C T A milder and efficient method was described for the synthesis of cis-1-(2-(4-(trifluoromethyl) phenyl)-1, 2, 3, 4-tetrahydroquinolin-4-yl) pyrrolidin-2-ones/azepan-2-ones (3a-d, 4a-d) via imino Diels-Alder ... Read More »

Anticancer Potential of Triaryl Methane

C. Sherlina Daphny*, P. Selvamani, S. Latha Department of Pharmaceutical Technology, Anna University Chennai, Regional office, BIT Campus, Tiruchirappalli, India-620 024. NCADDD, 25 July 2014, Organized by Department of Pharmaceutical Technology, Anna University, BIT Campus, Tiruchirappalli–620024, Tamil Nadu, India Abstract A derivative of Triaryl methane CRR- 638 was evaluated for their anticancer potential in lung cancer (A549) cells as In vitro model. ... Read More »

The Bioactive Compounds obtained from the Tomatoes (Solanum lycopersicum L.) act as Potential Anticancer agents against the Human Cervicle Adenocarcinoma

Asish Bhaumik*1, M. Upender Kumar1, P. Sravan Kumar2, Kaleem Ahmed Khan2, Ch. Srinivas3 1Department of Pharmaceutical Chemistry, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 2Department of Pharmacology, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. 3Department of Pharmaceutical Analysis, Teja College of Pharmacy, Kodad, Nalgonda-508206, Telangana, India. NCADDD, 25 July 2014, Organized by Department of Pharmaceutical Technology, Anna University, BIT Campus, ... Read More »

1H-1, 2, 4,-Triazole Having Significant Pharmacological Activities

Author Details Sakshi Gupta*, Dharmendra Kumar Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Baghpat bypass crossing, NH-58, Delhi-Roorkee, Highway, Meerut-250005, U. P., India E-mail: sakshi.mpharm2011@gmail.com Abstract In the last few years, heterocyclic compounds have attracted strong interest and a lot of work has been done on triazole ring. Many different derivatives have been prepared from it which ... Read More »

Evaluation of Proximate Screening of Phyllanthus Amarus

ABOUT AUTHOR Shirish S. Pingale*, Shrikant S. Shewale, Dilip B Satpute Department of Chemistry, Gramonnati Mandal’s, Arts Com. and Science College Narayangaon, Pune Abasaheb Garware College, Pune (Affiliated to University of Pune) E-mail: drsspingale@gmail.com ABSTRACT Natural products have traditionally provided many of the drugs in use. Despite the achievement of synthetic chemistry and advances towards rational drug design, natural products ... Read More »

Synthesis and characterization of 3-((5-phenyl-1, 3, 4-oxadiazol-2-yl)Methyl amino)-2-methyl quinazolin-4(3H)-one

About author : Ramesh Dhani JNTUA – OTRI, Anantapur, India Dept.of  Pharmaceutical Chemistry E-mail: dhanipharmachem@gmail.com ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, ... Read More »

ANALGESIC ACTIVITY OF 3-[(5-SUBSTITUED) – 1, 3, 4 OXADIAZOLE-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONES

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: dhanipharmachem@gmail.com ABSTRACT:  Heterocyclic drug having wide spectrum of activity, Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, antihistaminic, anticancer and so on. All the synthesized quinazolinone derivatives were confirmed preliminarily by M.P and TLC ... Read More »

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