Tuesday , 22 October 2019

Tag Archives: accuracy

Development of new simultaneous RP-HPLC method for the estimation of Dapagliflozin and Saxagliptin in tablet dosage form

M. Kavitha*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr.K.V.Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim of present research work made to develop and validate RP-HPLC method for the simultaneous estimation of Dapagliflozin and Saxagliptin in bulk and combined dosage form. The optimized mobile phase was consists of 0.1% ... Read More »

Development of New simultaneous RP-HPLC method for the estimation of Pentazocine HCl and Naloxone HCl in tablet dosage form

M. Sowbhagya Lakshmi*, C.S. Parameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T The aim of present research work made to develop and validate RP-HPLC method for the simultaneous estimation of Pentazocaine and Naloxone in bulk and combined dosage form. The optimized mobile phase was ... Read More »

Method Development and Validation for the Assay of Nebivolol Tablets by using RP-HPLC

1N. Kalpana Devi*, 2Pradeep Reddy, 3D.S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3 Vikas Institite of Pharmaceutical Sciences, Rajahmundary ABSTRACT A simple, precise, and accurate gradient reversed-phase (RP)  high-performance liquid chromatographic (HPLC) assay method was developed and validated for determination of nebivolol in tablet dosage forms. gradient RP-HPLC separation was achieved on a Phenomenex, kinetex ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form

V. Haribaskar, Ramesh Dhani, B. Swathi* Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, 5µ with flow rate 1ml/min using ... Read More »

Analytical Method Development and Validation for the Estimation of Erlotinib Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Gobala Krishnan P*, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy & Research centre, Nellore, Andhra Pradesh, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Erlotinib hydrochloride by using the HPLC method for Erlotinib hydrochloride as per ICH Guide lines. Shimadzu LC-2010 series ... Read More »

Method development and validation for the simultaneous estimation of Nebivolol hydrochloride and S (-) Amlodipine besilate in tablet dosage form by RP – HPLC

About author Prabhakaran. V.*, Sekar. S., Baskar.E., Raghuprasath. V.R. Formulation Research and Development Department, The Madras Pharmaceuticals, Karapakkam, Chennai, Tamil Nadu, India. Email: rnd@madraspharma.com ABSTRACT High Performance Liquid Chromatography method was developed and validated in a simple, specific and precise manner for Nebivolol HCl and Amlodipine besilate in a combined solid dosage form. Nebivolol hydrochloride, a long acting, cardioselective β ... Read More »

A COMPARISION OF ANALYTICAL METHOD VALIDATION PROCEDURES

About author: Chinmaya Keshari Sahoo* Research Scholar,Dept. of Pharmaceutics, OUCT, Osmania University,A.P, India *e-mail: sahoo.chinmaya83@gmail.com INTRODUCTION : Analytical method validation is a regulatory requirement that refers to the evaluation and proving that the selected analytical method shall ensure reproducible and reliable results adequate for the intended purpose.The process of analytical method validation should demonstrate that the method is fit for ... Read More »

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