Tuesday , 27 October 2020

Tag Archives: 4-Oxadiazole

Synthesis, Characterization, Biological Evaluation and Docking studies of 2-(benzyl sulfonyl)-5-(3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazole Derivatives

G. Govindu*, D. Rajesh, P. Raveendra Reddy, L.K. Ravindranath Department of chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P-India A B S T R A C T New novel derivatives of 2-((4- substituted benzyl)sulfonyl)-5-(3-(4-( substituted phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl)-1,3,4-oxadiazoles  (9a-l as per scheme-I)were prepared by condensation of 2-(4-hydrazinylpyrimidin-5-yl)-5-((4-substituted benzyl)sulfonyl)-1,3,4-oxadiazole (8a-f) with various 4-substituted benzoic acids. The synthon 8a-f were obtained by the refluxing of 2-(4-chloropyrimidin-5-yl)-5-((4-substituted ... Read More »

Various Synthesis Methods of 1,3,4-Oxadiazolederivatives: A Review

M Somashekhar*, R B Kotnal Department of Pharmaceutical Chemistry, Bldea’s College of Pharmacy, Vijaypur-586101. A B S T R A C T Heterocyclic molecules such as Oxadiazoles have been synthesized and evaluated for medical and agricultural activities. The disubstituted Oxadiazoles have executed a range of pharmacologic activities. 1,3,4-oxadiazole and 1,2,4-oxadiazole are better known, and more widely studied by researchers Among ... Read More »

Synthesis Charecterization and biological evaluation of 1-(5-(4-aminobenzoyl) -2,2-dimethyl-1,3,4-Oxadiazole-3(2H)-yl)ethanone

 V. Prabhakar1*, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2, V. Krishna Murthy Naik2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A.P, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu–515003, A.P, India A B S T R A C T Synthesis of 1,3,4 oxadiazole  derivatives containing aromatic rings were synthesised by the condensation of ... Read More »

Synthesis and Antimicrobial Activity Evaluation of Poly ethylen imine (PEI) Dendrimer modified with 1,2,4-oxadiazole derivatives

Author Details Maziar Mansouji Avval1*, V. Srinivasa Murthy 2, S.Shashikanth1 1Department of Studies in Chemistry, University of Mysore, Manasagangorti 570006, India. 2BNM Institute of technology, Bhanashankari, Bangalore, 560 076, India. Abstract Dendrimers have wide range of applications in industry, Pharmaceutical and medicine. Oxadiazole compounds also have many applications in Pharmaceutical and medicine. Modification of dendrimers which have many branches like ... Read More »

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