Wednesday , 19 September 2018

Synthesis of Some Substituted Quinazoline Moieties: A Review

M. A. Hameed Sadiq1*, Shoaib Patel2, Amol S. Dighe1, Rashmi D. Wani2, Bhagyashree P. Gaikwad2, Prashant Katiyar2, Shriram H. Bairagi2
1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, India- 413736.

2Department of Pharmaceutical Chemistry, Ideal College of Pharmacy & Research, Kalyan, India- 421306.

A B S T R A C T
Quinazoline is an aza derivative of the quinoline, it is also known as 1,3-diazanaphthalene. It has broad spectrum of activity which are anti-inflammatory, anti-bacterial, anti-microbial, anti-HIV, anti-cancer, and many more due to these biological effects it has drawn more interest in synthesis and derivatization of this moiety as much as possible. As the quinazoline is a promising molecule we have focused on the synthesis of this moiety by various ways.

Keywords: Quinazoline, quinazolinone, quinazolone.

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