Thursday , 15 November 2018

Synthesis of N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide

El Houssine Mabrouk1
1Laboratory of Organic Chemistry, Faculty of Sciences DharElMehraz, University Sidi Mohamed Ben Abdellah, Fez, B.P.:1796-Fès Atlas, Morocco

ABSTRACT
The title compound, N-(3-Oxo-2,4-dihydro-1H-quinoxalin-2-yl)benzamide2, was synthesized in high yield, via N-alkylation reaction of methyl 2-azido-2-benzamidoacetate or methyl 2-bromo-2-benzamidoacetate with o-phenylenediaminein acetone, with the presence of diisopropylethylamine(DIEPA) as a base. The structure of the prepared compound was characterized by 1H, 13C NMR in addition to MS.
Keywords:o-Phenylenediamine, heterocyclic compounds, Quinoxaline, N-alkylation.

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